Pain relief technique for patients undergoing breast reduction surgery

Bilateral Rhomboid Intercostal Block Versus Erector Spinae Plane Block for Perioperative Analgesia in Patients Undergoing Bilateral Reduction Mammoplasty

Not applicable Interventional Zagazig University · NCT06225895

This study is testing two different pain relief techniques to see if they can help people aged 18-65 recover more comfortably after breast reduction surgery while using fewer opioids.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment72 (estimated)
Ages18 Years to 65 Years
SexFemale
SponsorZagazig University Government
Locations2 sites (Zagazig, Alsharqia and 1 other locations)
Trial IDNCT06225895 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of bilateral rhomboid intercostal blocks and erector spinae plane blocks for managing postoperative pain in patients undergoing bilateral reduction mammoplasty. The study aims to minimize the reliance on opioids, which can have significant side effects, by utilizing regional anesthesia techniques that are easier and safer. Participants will receive general anesthesia along with the nerve blocks to assess their impact on pain management and recovery. The trial focuses on patients aged 18-65 with specific health criteria undergoing elective surgery.

Who should consider this trial

Good fit: Ideal candidates are women aged 18-65 with a BMI of 35 or less, undergoing elective bilateral reduction mammoplasty.

Not a fit: Patients with certain medical conditions, such as heart disease or those on specific medications, may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve postoperative pain management and recovery for patients undergoing breast reduction surgery.

How similar studies have performed: Other studies have shown promising results with similar regional anesthesia techniques, suggesting potential for success in this trial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient acceptance.
* Age 18-65 years old.
* BMI ≤ 35 kg/m2
* ASA I - II.
* Elective bilateral reduction mammoplasty surgery under general anesthesia.
* Duration of surgery within five hours

Exclusion Criteria:

* Patients on anti-platelet, anticoagulant, or B blocker drugs.
* Patients with acute decompensated heart failure, hypertension, heart block, coronary disease, Asthma
* History of allergy to the local anesthetics (LA) agents used in this study,
* Skin lesion at the needle insertion site,
* Those with bleeding disorders, sepsis, liver disease, psychiatric disorders, and pregnancy.

Where this trial is running

Zagazig, Alsharqia and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AnalgesiaRhomboid Intercostal BlockErector Spinae Plane BlockReduction Mammoplasty
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.