Pain relief methods for low back pain

Efficacy and Duration of Pain Relief in Transforaminal and Lumbar Sympathetic Blocks

NA · Bezmialem Vakif University · NCT06438952

This study tests whether combining steroid injections with a specific nerve block can provide better and longer-lasting pain relief for people with low back pain from a herniated disc compared to just using steroid injections alone.

Quick facts

PhaseNA
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorBezmialem Vakif University (other)
Locations2 sites (Istanbul and 1 other locations)
Trial IDNCT06438952 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness and duration of pain relief provided by transforaminal steroid injections combined with lumbar sympathetic blockade in patients suffering from low back pain, particularly those with lumbar disc herniation. It aims to compare the outcomes of this combined approach against transforaminal steroid injections alone. The study will assess pain levels using standardized questionnaires and numerical rating scales to determine the impact of the interventions on postoperative pain management.

Who should consider this trial

Good fit: Ideal candidates for this study are patients with low back pain due to lumbar disc herniation who have undergone facet joint and transforaminal injections.

Not a fit: Patients with known allergies to the treatment drugs, severe anatomical variations, or uncontrolled comorbidities may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more effective pain management strategy for patients with low back pain, improving their quality of life.

How similar studies have performed: Other studies have shown promising results with similar interventional approaches, suggesting potential efficacy in pain management.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ASA I-II-III
* Patients who underwent facet joint injection and transforaminal injection due to lumbar disc herniation

Exclusion Criteria:

* Patients with known allergies to the drugs to be used in treatment
* Infection near the puncture site
* Known coagulation disorders
* Patients with internal fixation or severe anatomical variation such as scoliosis and tumor
* History of sympathetic chemical or thermal neurolysis
* Alcohol and drug use
* Disorder of consciousness
* Liver failure, renal failure, advanced cardiac failure
* Uncontrolled diabetes mellitus
* Morbid obesity (body mass index (BMI) \> 35 kg m-2)
* Female patients during pregnancy and breastfeeding
* Not approving the informed consent form

Where this trial is running

Istanbul and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Low Back Pain, Lumbar Disc Herniation, Transforaminal Steroid İnjection, Lumbar Sympathetic Blockade, Neuropathic Pain Questionnaire, Numerical Rating Scale

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.