Pain relief for kidney stones using a specific nerve block technique
Erector Spinae Plane Block for Uncomplicated Renal Colic
This study tests if a specific nerve block can help people with kidney stone pain feel better without using opioids.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Michigan Academic / other |
| Locations | 1 site (Ann Arbor, Michigan) |
| Trial ID | NCT05625802 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of the Erector Spinae Plane Block (ESPB) in alleviating pain associated with renal colic caused by kidney stones. Participants will receive ropivacaine through this nerve block to assess pain relief and monitor any potential side effects. The study aims to provide a non-opioid pain management option for patients presenting to the emergency department with kidney stone pain. The trial will include patients who have confirmed kidney stones and have received initial pain medication in the emergency department.
Who should consider this trial
Good fit: Ideal candidates are adults with confirmed kidney stones who have received pain medication in the emergency department.
Not a fit: Patients who are pregnant, breastfeeding, or have certain medical conditions such as coagulopathy or active urinary tract infections may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could offer effective pain relief for patients suffering from kidney stones without the use of opioids.
How similar studies have performed: Other studies have shown promising results with similar nerve block techniques for pain management, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Imaging confirmation of urolithiasis on the index encounter or prior encounter within 7 days * Patient received one dose of parenteral pain medication in the emergency department (ED) Exclusion Criteria: * Pregnancy or breastfeeding * Prisoner or incarcerated individual * Therapeutic anticoagulation or coagulopathy. * Active treatment for urinary tract infection (either acute infection or chronic therapy) * Prior spinal surgery in the thoracic region * Allergy to local anesthetic or prior local anesthetic * Soft tissue infection overlying the injection site * Positive for coronavirus * Inability to communicate verbally or read/write in English * Currently taking strong CYP1A2 inhibitor (fluvoxamine, amiodarone, fluoroquinolones, etc.) * Glucose-6-phosphate dehydrogenase deficiency (G6PD)
Where this trial is running
Ann Arbor, Michigan
- The University of Michigan — Ann Arbor, Michigan, United States (Recruiting)
Study contacts
- Study coordinator: Carmen Colmenero Mahmood
- Email: cico@med.umich.edu
- Phone: 734-647-0574
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.