Pain relief after robotic surgery for endometriosis using nerve block

Superior Hypogastric Nerve Plexus Block With Bupivacaine for Postoperative Pain Reduction Following Robotic Assisted Resection of Endometriosis: A Randomized Control Trial

Phase 4 Interventional Baylor College of Medicine · NCT06577233

This study tests if a special nerve block can help women feel less pain and use fewer pain medications after having robotic surgery for endometriosis.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 65 Years
SexFemale
SponsorBaylor College of Medicine Academic / other
Locations1 site (Houston, Texas)
Trial IDNCT06577233 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of a superior hypogastric nerve plexus block with bupivacaine in reducing postoperative pain and opioid use in women undergoing robotic surgery for endometriosis. Patients scheduled for this surgery will be informed about the trial during their preoperative visit and can choose to participate. Those who consent will be randomly assigned to either the treatment group receiving the nerve block or a placebo group, while their medical records will be accessed for demographic and surgical data. The study seeks to provide a multimodal approach to pain management in this patient population.

Who should consider this trial

Good fit: Ideal candidates are women aged 18-65 scheduled for robotic-assisted resection of endometriosis.

Not a fit: Patients who are pregnant, under 18, or part of vulnerable populations may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce postoperative pain and reliance on opioids for women undergoing surgery for endometriosis.

How similar studies have performed: Previous studies have shown positive outcomes with nerve blocks in gynecologic surgeries, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18-65 years old
* Scheduled to undergo a robotic assisted resection of endometriosis

Exclusion Criteria:

* Subjects who are part of a vulnerable population will be excluded including those who are prisoners, younger than 18 years old, pregnant, individuals with mental disabilities or cognitive impairment.

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions EndometriosisEndometriosis, Postoperative Pain, Robotic Surgery
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.