Pain neuroscience education and its effects on pain levels and BDNF.
Effect of Therapeutic Education on Pain Levels and Brain Neurotrophic Factor in Patients With Chronic Pain.
This study tests if a group program teaching people about pain can help those with chronic pain feel better and improve their quality of life.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 66 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Universidad Autonoma de Madrid Academic / other |
| Locations | 1 site (Madrid) |
| Trial ID | NCT05736172 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of a group-based pain neuroscience education program on patients suffering from chronic musculoskeletal pain. The approach focuses on promoting neuroplasticity and restructuring maladaptive cognitions that contribute to persistent pain. By examining the relationship between brain-derived neurotrophic factor (BDNF) levels and pain perception, the study aims to establish a neurophysiological basis for therapeutic strategies in physiotherapy. Participants will be educated on pain mechanisms to potentially improve their quality of life.
Who should consider this trial
Good fit: Ideal candidates are males and females aged 18 to 65 years with chronic musculoskeletal pain lasting at least 3 months.
Not a fit: Patients with systemic, neurological, oncological, or inflammatory diseases, as well as those with psychiatric conditions or pregnancy, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide new therapeutic strategies to help patients manage chronic pain more effectively.
How similar studies have performed: Other studies have shown promising results with similar educational approaches in managing chronic pain, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * males and females aged 18 to 65 years with musculoskeletal pain for a minimum of 3 months * patients recruited by information pamphlets from the university clinic of the Rey Juan Carlos University, and CSEU La Salle * ability to perform all the clinical tests and to understand the study process, as well as to obtain informed consent. Exclusion Criteria: -Systemic, neurological, oncological or inflammatory diseases; psychiatric pathologies, pregnancy, type II diabetes.
Where this trial is running
Madrid
- Silvia Di Bonaventura — Madrid, Spain (Recruiting)
Study contacts
- Principal investigator: Silvia Di Bonaventura — Universidad Rey Juan Carlos
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.