Outcomes of VV-ECMO during emergency thoracic surgery
Official title: Prognostic Factors for 90-day Mortality in Patients Undergoing Veno-venous Extracorporeal Membrane Oxygenation for Emergency Thoracic Surgery
Run by Centre Hospitalier Universitaire, Amiens · NCT07016685 · Data updated 2026-11-12
This project tries to compare outcomes for adults who receive veno-venous ECMO during or after emergency chest surgery with patients who receive VV-ECMO for medical respiratory failure.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 380 (estimated) |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Status | Recruiting |
| Started | June 1, 2025 |
| Main results expected | November 2025 |
| Study ends | April 2026 |
| Registry record updated | June 13, 2025 |
| Trial ID | NCT07016685 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older who had VV-ECMO started during or after emergency thoracic surgery and who did not object to use of their medical data are the intended group for this analysis.
✕Probably not a fit
Pregnant patients, those supported with veno-arterial ECMO, people under legal protection, and patients never treated at the participating centers are not included and would not benefit from the study findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This retrospective multicenter observational project reviews records from two French university hospitals to compare clinical outcomes of adults who had VV-ECMO initiated during or after emergency thoracic surgery with a control cohort treated with VV-ECMO for medical respiratory failure. Investigators will collect demographics, perioperative details, ECMO duration, complications, and survival data to identify prognostic factors. The analysis focuses on differences in morbidity, mortality, and predictors of outcome between the surgical and medical VV-ECMO groups. Data come from CHU Amiens-Picardie and CHU Dijon and will be analyzed using standard cohort methods.
Why it matters
Potential benefit: If successful, this work could help clinicians recognize which patients benefit most from perioperative VV-ECMO and improve decision-making around emergency thoracic surgery support.
How similar studies have gone: VV-ECMO is well established for medical respiratory failure such as ARDS, but its perioperative use in emergency thoracic surgery is less well studied and evidence is largely limited to small retrospective series.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults ≥ 18 years * VV-ECMO initiated during or after emergency thoracic surgery * No opposition to data use Exclusion Criteria: * Pregnant women * Veno-Arterial ECMO patients * Patients under legal protection
Where it's running
-
CHRU Amiens
Amiens, France Recruiting
Study contacts
- Study coordinator: Christophe Beyls, MD
- Email: beyls.christophe@chu-amiens.fr
- Phone: 33+3 22 08 78
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.