Outcomes of VV-ECMO during emergency thoracic surgery
Prognostic Factors for 90-day Mortality in Patients Undergoing Veno-venous Extracorporeal Membrane Oxygenation for Emergency Thoracic Surgery
This project tries to compare outcomes for adults who receive veno-venous ECMO during or after emergency chest surgery with patients who receive VV-ECMO for medical respiratory failure.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 380 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Trial ID | NCT07016685 on ClinicalTrials.gov |
What this trial studies
This retrospective multicenter observational project reviews records from two French university hospitals to compare clinical outcomes of adults who had VV-ECMO initiated during or after emergency thoracic surgery with a control cohort treated with VV-ECMO for medical respiratory failure. Investigators will collect demographics, perioperative details, ECMO duration, complications, and survival data to identify prognostic factors. The analysis focuses on differences in morbidity, mortality, and predictors of outcome between the surgical and medical VV-ECMO groups. Data come from CHU Amiens-Picardie and CHU Dijon and will be analyzed using standard cohort methods.
Who should consider this trial
Good fit: Adults aged 18 or older who had VV-ECMO started during or after emergency thoracic surgery and who did not object to use of their medical data are the intended group for this analysis.
Not a fit: Pregnant patients, those supported with veno-arterial ECMO, people under legal protection, and patients never treated at the participating centers are not included and would not benefit from the study findings.
Why it matters
Potential benefit: If successful, this work could help clinicians recognize which patients benefit most from perioperative VV-ECMO and improve decision-making around emergency thoracic surgery support.
How similar studies have performed: VV-ECMO is well established for medical respiratory failure such as ARDS, but its perioperative use in emergency thoracic surgery is less well studied and evidence is largely limited to small retrospective series.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults ≥ 18 years * VV-ECMO initiated during or after emergency thoracic surgery * No opposition to data use Exclusion Criteria: * Pregnant women * Veno-Arterial ECMO patients * Patients under legal protection
Where this trial is running
Amiens
- CHRU Amiens — Amiens, France (Recruiting)
Study contacts
- Study coordinator: Christophe Beyls, MD
- Email: beyls.christophe@chu-amiens.fr
- Phone: 33+3 22 08 78
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.