Outcomes of colorectal cancer treated with natural orifice surgery
Short-term and Long-term Outcomes of Colorectal Cancer Treated With Natural Orifice Specimen Extraction Surgery : a National Registry-based Study
This study looks at how well a new, less invasive surgery called natural orifice specimen extraction works for people with colorectal cancer, by checking their recovery and outcomes after the procedure.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 8000 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Cancer Institute and Hospital, Chinese Academy of Medical Sciences Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT06350370 on ClinicalTrials.gov |
What this trial studies
This study evaluates the short-term and long-term outcomes of colorectal cancer patients who undergo natural orifice specimen extraction surgery (NOSES). It is a large retrospective analysis involving nearly 100 centers across China, aiming to gather comprehensive data on the safety and feasibility of this minimally invasive surgical technique. By analyzing patient demographics, perioperative data, and postoperative outcomes, the study seeks to provide robust evidence to support the clinical application of NOSES in treating colorectal cancer.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with a pathological diagnosis of primary malignant tumors in the colon or rectum who meet the criteria for NOSES.
Not a fit: Patients whose postoperative diagnosis does not confirm primary malignant tumors in the colon or rectum will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding and application of minimally invasive surgical techniques for colorectal cancer, potentially leading to better patient outcomes.
How similar studies have performed: While NOSES is gaining recognition, this study aims to provide the first large-scale evidence-based evaluation of its feasibility and safety, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Pathological diagnosis of primary malignant tumor in the colon or rectum; 2. The surgery meets the definition in the "Consensus of NOSES Experts in Colorectal Cancer"; Exclusion Criteria: 1. Postoperative pathological diagnosis does not belong to primary malignant tumors in the colon or rectum; 2. The surgery does not meet the definition in the "Consensus of NOSES Experts in Colorectal Cancer".
Where this trial is running
Beijing, Beijing Municipality
- Cancer Hospital Chinese Academy of Medical Sciences — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Study coordinator: Xishan Wang
- Email: wxshan_cams@163.com
- Phone: +8613552367779
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.