Osteoporosis Fracture Prevention (OPTIONS) program to support recovery after a broken hip or leg.
Official title: Effectiveness of an Multi-Modal Intervention for Transitions of Care After Lower Limb Fracture
Run by Brigham and Women's Hospital · NCT06731608 · Data updated 2026-11-12
This project tests whether a combined program of tailored exercise, healthy nutrition, and bone‑strengthening medicines with clinician decision support helps people 65+ who break a hip or leg recover in a skilled nursing facility and avoid future fractures.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 1344 (estimated) |
| Sponsor | Brigham and Women's Hospital Academic / other |
| Locations | 2 sites (Baltimore, Maryland and 1 other locations) |
| Status | Recruiting |
| Started | January 16, 2026 |
| Main results expected | August 1, 2028 |
| Study ends | February 1, 2029 |
| Registry record updated | January 29, 2026 |
| Trial ID | NCT06731608 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are community‑dwelling adults aged 65 or older who are admitted to a participating SNF for rehabilitation after a lower‑limb fragility fracture and are expected to discharge back to the community, are English or Spanish speakers, and have adequate cognition to participate (BIMS score >7).
✕Probably not a fit
Patients receiving hospice or end‑of‑life care, those with serious cognitive impairment (BIMS 0–7), non‑English/non‑Spanish speakers, or those with SNF stays under seven days or not expected to return to the community are unlikely to benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Investigators will introduce OPTIONS, an integrated multi‑modal intervention that uses clinical decision support for clinicians and tailored education for patients and care partners to increase use of exercise, nutrition, and osteoporosis medications during and after skilled nursing facility (SNF) rehabilitation. The program targets older adults who were living in the community before a lower‑limb fragility fracture and who are admitted to participating SNFs for rehabilitation with an expected discharge back to the community. Implementation will be done in partnership with health‑IT systems (including PointClickCare) to deliver decision support and coordinate care across the SNF and transition home. Outcomes include uptake and sustained use of evidence‑based interventions and improved recovery and fracture prevention across the care transition.
Why it matters
Potential benefit: If successful, the program could increase use of proven therapies after a hip or leg fracture, reduce future fractures, and improve recovery and independence for older adults.
How similar studies have gone: Components such as exercise, nutrition, and osteoporosis medications have shown benefit in prior studies, but embedding them via clinical decision support across SNFs and transitions is a relatively novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥65 years old * Community-dwelling at the time of fracture * Admission to a participating SNF for rehabilitation following a lower limb fragility fracture, including pelvic fractures * Expected discharge to the community (home or assisted living) Exclusion Criteria: * Not English or Spanish speaker * Admission Brief Interview for Mental Status (BIMS) score 0-7 * SNF length of stay \< 7 days * Regular access to a working telephone or other communication device * Receiving hospice or end-of-life care
Where it's running
-
University of Maryland, Baltimore, Department of Epidemiology and Public Health, Division of Gerontology
Baltimore, Maryland, United States Recruiting -
Brigham and Women's Hospital
Boston, Massachusetts, United States Recruiting
Study contacts
- Principal investigator: Denise Orwig, PhD — University of Maryland, Baltimore
- Study coordinator: Patricia Dykes, RN, PhD
- Email: pdykes@bwh.harvard.edu
- Phone: 617-850-5748
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.