Clinical trial Recruiting at 1 site Observational Ages 18 and up Women only

Origins, features, and effects of preeclampsia on mother and baby

Official title: Face to Face With Preeclampsia: Understanding Its Origin, Characteristics and Effects on Mother and Baby

Run by Medical University of Graz · NCT07513558 · Data updated 2026-11-12

This project will follow pregnant women diagnosed with preeclampsia through late pregnancy, delivery, and early postpartum to collect clinical data and biological samples to see how preeclampsia affects mothers and their babies.

More Pregnancy trials

Quick facts

Study typeObservational
Ages18 Years and up
SexWomen only
Enrollment250 (estimated)
SponsorMedical University of Graz
Academic / other
Locations1 site (Graz)
StatusRecruiting
StartedMarch 1, 2026
Main results expectedMarch 2031
Study endsMarch 2036
Registry record updatedApril 13, 2026
Trial IDNCT07513558 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Pregnant women aged 18 or older with a current clinical diagnosis of preeclampsia at any gestational age and no major fetal anomalies are the ideal candidates.

Probably not a fit

Women without preeclampsia and those with fetal genetic abnormalities (who are excluded) are not eligible and, because the project is observational, participants should not expect direct therapeutic benefit from joining.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-center observational cohort enrolling about 50 pregnant women with clinically diagnosed preeclampsia per year at the Department of Obstetrics and Gynecology, Medical University of Graz. Participants attend up to four time points (diagnosis, late pregnancy, delivery sampling, and an 8–12 week postpartum visit) for clinical data collection, physical measurements, and biological sample banking. The protocol excludes pregnancies with major fetal anomalies and focuses on standardized phenotyping to link maternal clinical features, placental and blood biomarkers, and early neonatal outcomes. Collected data and samples aim to support detailed analyses of disease mechanisms and early-life consequences for mother and child.

Why it matters

Potential benefit: If successful, this cohort could improve understanding of preeclampsia mechanisms and help develop better prediction, monitoring, and long-term care strategies for affected mothers and offspring.

How similar studies have gone: Longitudinal pregnancy cohorts have previously improved understanding of preeclampsia risk factors and biomarkers, but mechanistic links and long-term effects remain incompletely understood.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ongoing pregnancy with preeclampsia regardless the gestational age diagnosed for PE

Exclusion Criteria:

* Maternal or fetal genetic abnormalities

Where it's running

  • Department of Obstetrics and Gynecology, Medical University of Graz
    Graz, Austria
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.