Origins, features, and effects of preeclampsia on mother and baby
Face to Face With Preeclampsia: Understanding Its Origin, Characteristics and Effects on Mother and Baby
This project will follow pregnant women diagnosed with preeclampsia through late pregnancy, delivery, and early postpartum to collect clinical data and biological samples to see how preeclampsia affects mothers and their babies.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Medical University of Graz Academic / other |
| Locations | 1 site (Graz) |
| Trial ID | NCT07513558 on ClinicalTrials.gov |
What this trial studies
This is a prospective, single-center observational cohort enrolling about 50 pregnant women with clinically diagnosed preeclampsia per year at the Department of Obstetrics and Gynecology, Medical University of Graz. Participants attend up to four time points (diagnosis, late pregnancy, delivery sampling, and an 8–12 week postpartum visit) for clinical data collection, physical measurements, and biological sample banking. The protocol excludes pregnancies with major fetal anomalies and focuses on standardized phenotyping to link maternal clinical features, placental and blood biomarkers, and early neonatal outcomes. Collected data and samples aim to support detailed analyses of disease mechanisms and early-life consequences for mother and child.
Who should consider this trial
Good fit: Pregnant women aged 18 or older with a current clinical diagnosis of preeclampsia at any gestational age and no major fetal anomalies are the ideal candidates.
Not a fit: Women without preeclampsia and those with fetal genetic abnormalities (who are excluded) are not eligible and, because the project is observational, participants should not expect direct therapeutic benefit from joining.
Why it matters
Potential benefit: If successful, this cohort could improve understanding of preeclampsia mechanisms and help develop better prediction, monitoring, and long-term care strategies for affected mothers and offspring.
How similar studies have performed: Longitudinal pregnancy cohorts have previously improved understanding of preeclampsia risk factors and biomarkers, but mechanistic links and long-term effects remain incompletely understood.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ongoing pregnancy with preeclampsia regardless the gestational age diagnosed for PE Exclusion Criteria: * Maternal or fetal genetic abnormalities
Where this trial is running
Graz
- Department of Obstetrics and Gynecology, Medical University of Graz — Graz, Austria (Recruiting)
Study contacts
- Study coordinator: Christina Stern, Dr.med
- Email: christina.stern@medunigraz.at
- Phone: +43 316 385 86306
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.