Origins, features, and effects of preeclampsia on mother and baby
Official title: Face to Face With Preeclampsia: Understanding Its Origin, Characteristics and Effects on Mother and Baby
Run by Medical University of Graz · NCT07513558 · Data updated 2026-11-12
This project will follow pregnant women diagnosed with preeclampsia through late pregnancy, delivery, and early postpartum to collect clinical data and biological samples to see how preeclampsia affects mothers and their babies.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 250 (estimated) |
| Sponsor | Medical University of Graz Academic / other |
| Locations | 1 site (Graz) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | March 2031 |
| Study ends | March 2036 |
| Registry record updated | April 13, 2026 |
| Trial ID | NCT07513558 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Pregnant women aged 18 or older with a current clinical diagnosis of preeclampsia at any gestational age and no major fetal anomalies are the ideal candidates.
✕Probably not a fit
Women without preeclampsia and those with fetal genetic abnormalities (who are excluded) are not eligible and, because the project is observational, participants should not expect direct therapeutic benefit from joining.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, single-center observational cohort enrolling about 50 pregnant women with clinically diagnosed preeclampsia per year at the Department of Obstetrics and Gynecology, Medical University of Graz. Participants attend up to four time points (diagnosis, late pregnancy, delivery sampling, and an 8–12 week postpartum visit) for clinical data collection, physical measurements, and biological sample banking. The protocol excludes pregnancies with major fetal anomalies and focuses on standardized phenotyping to link maternal clinical features, placental and blood biomarkers, and early neonatal outcomes. Collected data and samples aim to support detailed analyses of disease mechanisms and early-life consequences for mother and child.
Why it matters
Potential benefit: If successful, this cohort could improve understanding of preeclampsia mechanisms and help develop better prediction, monitoring, and long-term care strategies for affected mothers and offspring.
How similar studies have gone: Longitudinal pregnancy cohorts have previously improved understanding of preeclampsia risk factors and biomarkers, but mechanistic links and long-term effects remain incompletely understood.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ongoing pregnancy with preeclampsia regardless the gestational age diagnosed for PE Exclusion Criteria: * Maternal or fetal genetic abnormalities
Where it's running
-
Department of Obstetrics and Gynecology, Medical University of Graz
Graz, Austria Recruiting
Study contacts
- Study coordinator: Christina Stern, Dr.med
- Email: christina.stern@medunigraz.at
- Phone: +43 316 385 86306
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Maternal insulin and fat metabolism in pregnancies at risk for preeclampsia and gestational diabetes
This project will try to see if insulin resistance and how the body burns fats early in pregnancy predict later preeclampsia or gestational diabetes in people at higher risk.
-
Examining how aspirin metabolism relates to metabolic dysfunction in pregnant individuals at risk of preeclampsia
This study is trying to see how the way pregnant people process aspirin relates to their metabolic health and the health of their babies, especially for those at risk of preeclampsia.
-
Using progesterone to improve outcomes for mothers and babies with preeclampsia
This study is testing if a hormone treatment can help improve health outcomes for mothers and their babies who have preeclampsia before 34 weeks of pregnancy.
-
Pregnant Women Living with HIV on Bictegravir/Emtricitabine/Tenofovir Alafenamide
This study looks at how B/F/TAF is used in pregnant women with HIV and whether it helps maintain viral suppression from before conception through delivery.
-
Pelvic Floor Training and a Modified Lumbopelvic Belt for Symphysis Pubis Pain in Pregnancy
This study tests whether pelvic floor muscle training plus a modified lumbopelvic belt can reduce pain and improve function for pregnant women with symphysis pubis pain.
-
Effective Communication in VBAC Counseling
This study tests how clearly doctors and midwives explain VBAC options during prenatal visits and whether patients feel understood.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.