Oral antibiotics before colorectal surgery in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial compares preoperative oral antibiotics to no oral antibiotics in pediatric patients undergoing elective colorectal procedures. All participants receive standard surgical care and postoperative management per hospital guidelines. The trial focuses on outcomes such as surgical site infection and anastomotic leakage to determine if preoperative antibiotics can reduce postoperative complications and promote faster recovery. Eligible children include those planned for colostomy closure or pull-through procedures for conditions like anorectal malformation or Hirschsprung disease, among others. The study aims to provide evidence to guide preoperative bowel preparation in pediatric colorectal surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Children with colostomy planned for colostomy closure or pull through procedure for conditions including

1. Anorectal malformation
2. Hirschsprung's Disease
3. Perianal Infections
4. Perineal Trauma
5. Any other condition requiring diversion colostomy

Exclusion Criteria:

1. Children with small bowel stomas
2. poor general condition (Malnutrition, immunodeficiency)
3. Previous attempt at repair of colostomy (Reversal/Pull through)

Where it's running

• University of Child Health Sciences, The Children's Hospital, Lahore
  Lahore, Punjab Province, Pakistan Recruiting

Study contacts

• Principal investigator: Mudassar Naveed, MBBS — University of Child Health sciences & The Children's Hospital, Lahore
• Study coordinator: Mudassar Naveed, MBBS
• Email: mudassarnaveed81@gmail.com
• Phone: +923214977599

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.