Optimizing treatment for brain-injured military personnel
Treatment Optimization of Brain-injured Warfighters: A Prescribed Sub-symptomatic Exercise Treatment
NA · United States Naval Medical Center, San Diego · NCT06561100
This study is testing a new exercise program to see if it can help active duty service members with mild brain injuries feel better and think more clearly.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 140 (estimated) |
| Ages | 18 Years to 55 Years |
| Sex | All |
| Sponsor | United States Naval Medical Center, San Diego (fed) |
| Locations | 1 site (Camp Pendleton, California) |
| Trial ID | NCT06561100 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of a prescribed sub-symptomatic adaptable exercise treatment (SAET) for active duty service members with mild traumatic brain injury (mTBI) and persistent cognitive complaints. Participants will be randomly assigned to receive either SAET or an active stretching control group (SCG) to assess the reduction of neurobehavioral symptoms and improvements in cognitive performance and physiological adaptation. The study aims to personalize the exercise treatment to meet the specific needs of service members while being adaptable to various clinical settings.
Who should consider this trial
Good fit: Ideal candidates are active duty service members aged 18 to 55 with a history of at least one mTBI and ongoing symptoms.
Not a fit: Patients who have sustained a TBI of any severity within the last month or have a history of severe neurological conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve recovery outcomes for military personnel suffering from mild traumatic brain injuries.
How similar studies have performed: Other studies have shown promising results with similar exercise-based interventions for mTBI, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Active duty, male or female, ages 18 to 55 * History of at least one mTBI sustained more than 1 month ago * Service members (SMs) with ongoing symptoms Exclusion Criteria: * SMs who sustained a TBI of any severity within 1 month of enrollment * History of moderate, severe, or penetrating TBI * Current substance use disorder * History of a neurological disease (e.g., multiple sclerosis, cerebral vascular accident, brain tumor, neurodegenerative disease, or neuro-motor disorder) * An acute orthopedic injury that limits the capacity to complete study procedures
Where this trial is running
Camp Pendleton, California
- Intrepid Spirit Center — Camp Pendleton, California, United States (RECRUITING)
Study contacts
- Principal investigator: Jason M Bailie, Phd — Traumatic Brain Injury Center of Excellence (TBICoE)
- Study coordinator: Jason M Bailie, PhD
- Email: jason.m.bailie.ctr@health.mil
- Phone: (760) 719-4202
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Mild Traumatic Brain Injury, Progressive Return to Activity, Warfighter Readiness