Optimizing treatment for anal suppurations in Crohn's disease
Analysis of Therapeutic Management Strategies for Anal Suppurations of Crohn's Disease
This study is testing different treatment options for people with Crohn's disease who have anal abscesses to see which ones work best for healing and improving their health over a year.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 440 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Rennes University Hospital Academic / other |
| Locations | 1 site (Rennes) |
| Trial ID | NCT04192825 on ClinicalTrials.gov |
What this trial studies
This study aims to identify the best therapeutic strategies for achieving complete clinical and anatomical remission of anal suppurations in patients with Crohn's disease over a 12-month period. It will analyze various treatment combinations, including immunosuppressants, biotherapies, antibiotics, and surgical interventions, to determine their effectiveness. The study emphasizes the importance of MRI evaluations in assessing treatment responses and aims to redefine management protocols for patients with anoperineal lesions. By focusing on both medical and surgical approaches, the study seeks to improve patient outcomes and satisfaction.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who are experiencing anal suppuration related to Crohn's disease and are scheduled for a drainage procedure.
Not a fit: Patients who are unable to undergo anesthesia or MRI examinations, or those with other priority health issues, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective treatment strategies for patients suffering from anal suppurations due to Crohn's disease.
How similar studies have performed: Previous studies have shown promising results with combined therapeutic approaches for similar conditions, indicating potential for success in this study.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Persons over 18 years of age * People suffering from anal suppuration of Crohn's disease for whom a drainage procedure is planned. * Person who has received written and oral information about the protocol and has not expressed opposition to participate in the study. Exclusion Criteria: * No one who is unable to have an anesthetic, structural or psychological examination by MRI and/or surgery. * Person planning a planned absence that could hinder participation in the research (travel abroad, relocation, impending transfer); * Person with an associated pathology that is a priority for care; * Vulnerable person (minors, persons under guardianship or curatorship, or deprived of their liberty by a judicial or administrative decision
Where this trial is running
Rennes
- Centre Hospitalier de Rennes — Rennes, France (Recruiting)
Study contacts
- Principal investigator: Laurent SIPROUDHIS, PH-PD — Rennes University Hospital
- Study coordinator: kristell COAT
- Email: kristell.coat@chu-rennes.fr
- Phone: 299282555
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.