Optimizing recovery in patients with alcohol-related liver cirrhosis
Disease and Outcomes in Alcohol Related Liver Cirrhosis - A Prospective Cohort Study of Optimized Remission
This study is testing if motivational interviews along with regular care can help people with alcohol-related liver cirrhosis improve their liver function and slow down the disease.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 350 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Copenhagen University Hospital, Hvidovre Academic / other |
| Locations | 1 site (Hvidovre, Capital Region) |
| Trial ID | NCT06866496 on ClinicalTrials.gov |
What this trial studies
This clinical trial focuses on patients diagnosed with alcohol-related liver cirrhosis, aiming to explore the effectiveness of motivational interviews combined with standard care to promote hepatic recompensation. The study will assess clinical and biochemical markers to predict and monitor improvements in liver function. By addressing the underlying causes of liver disease, the trial seeks to slow disease progression and potentially reverse cirrhosis. Participants will be closely monitored for complications associated with portal hypertension and overall health outcomes.
Who should consider this trial
Good fit: Ideal candidates are individuals with a clinical diagnosis of alcohol-related cirrhosis supported by biochemical tests and imaging.
Not a fit: Patients with uncertain diagnoses of alcohol-related cirrhosis or those who withdraw consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve liver health and reduce complications for patients with alcohol-related liver cirrhosis.
How similar studies have performed: While there have been studies exploring treatments for cirrhosis, this specific approach focusing on motivational interviews and biomarkers is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical suspicion of cirrhosis related to use of alcohol, supported by biochemistry and ultrasound or other imaging techniques. * Informed written consent. Exclusion Criteria: * The diagnosis of ALC is questioned with reasonable doubt. * Withdrawal of informed consent or no informed consent.
Where this trial is running
Hvidovre, Capital Region
- Copenhagen University Hospital Hvidovre — Hvidovre, Capital Region, Denmark (Recruiting)
Study contacts
- Principal investigator: Nina Kimer, MD, PhD — Gastroenheden, Hvidovre Hospital
- Study coordinator: Nina Kimer, MD, PhD
- Email: nina.kimer@regionh.dk
- Phone: +4538621968
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.