Optimizing recovery in patients with alcohol-related liver cirrhosis
Official title: Disease and Outcomes in Alcohol Related Liver Cirrhosis - A Prospective Cohort Study of Optimized Remission
Run by Copenhagen University Hospital, Hvidovre · NCT06866496 · Data updated 2026-11-12
This study is testing if motivational interviews along with regular care can help people with alcohol-related liver cirrhosis improve their liver function and slow down the disease.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 350 (estimated) |
| Sponsor | Copenhagen University Hospital, Hvidovre Academic / other |
| Locations | 1 site (Hvidovre, Capital Region) |
| Status | Recruiting |
| Started | December 22, 2024 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2034 |
| Registry record updated | March 10, 2025 |
| Trial ID | NCT06866496 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals with a clinical diagnosis of alcohol-related cirrhosis supported by biochemical tests and imaging.
✕Probably not a fit
Patients with uncertain diagnoses of alcohol-related cirrhosis or those who withdraw consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial focuses on patients diagnosed with alcohol-related liver cirrhosis, aiming to explore the effectiveness of motivational interviews combined with standard care to promote hepatic recompensation. The study will assess clinical and biochemical markers to predict and monitor improvements in liver function. By addressing the underlying causes of liver disease, the trial seeks to slow disease progression and potentially reverse cirrhosis. Participants will be closely monitored for complications associated with portal hypertension and overall health outcomes.
Why it matters
Potential benefit: If successful, this approach could significantly improve liver health and reduce complications for patients with alcohol-related liver cirrhosis.
How similar studies have gone: While there have been studies exploring treatments for cirrhosis, this specific approach focusing on motivational interviews and biomarkers is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical suspicion of cirrhosis related to use of alcohol, supported by biochemistry and ultrasound or other imaging techniques. * Informed written consent. Exclusion Criteria: * The diagnosis of ALC is questioned with reasonable doubt. * Withdrawal of informed consent or no informed consent.
Where it's running
-
Copenhagen University Hospital Hvidovre
Hvidovre, Capital Region, Denmark Recruiting
Study contacts
- Principal investigator: Nina Kimer, MD, PhD — Gastroenheden, Hvidovre Hospital
- Study coordinator: Nina Kimer, MD, PhD
- Email: nina.kimer@regionh.dk
- Phone: +4538621968
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.