Optimizing maintenance of fully implanted venous catheters for cancer patients

Maintenance Optimization of the Fully Implanted Venous Catheter

NA · Clinical Academic Center (2CA-Braga) · NCT05411666

This study is testing whether regularly cleaning implanted catheters with saline helps cancer patients more than not cleaning them at all.

Quick facts

PhaseNA
Study typeInterventional
Enrollment176 (estimated)
Ages18 Years and up
SexAll
SponsorClinical Academic Center (2CA-Braga) (other)
Drugs / interventionschemotherapy
Locations1 site (Braga)
Trial IDNCT05411666 on ClinicalTrials.gov

What this trial studies

This study evaluates the necessity and frequency of maintenance for fully implanted central venous catheters (CVCTI) used in cancer patients. It compares two approaches: maintaining the catheter with saline solution versus no maintenance at all. The goal is to clarify existing discrepancies in maintenance practices across different cancer centers and to establish a standardized approach. By assessing the outcomes of these two methods, the study aims to improve patient care and catheter management.

Who should consider this trial

Good fit: Ideal candidates are cancer patients over 18 years old who have undergone placement of a fully implanted central venous catheter for chemotherapy within the last 10 weeks.

Not a fit: Patients with metastases, those on anticoagulant medication, or individuals with a history of CVCTI-related adverse events may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more effective and standardized maintenance practices for central venous catheters, enhancing patient comfort and reducing complications.

How similar studies have performed: While there is ongoing debate regarding catheter maintenance practices, this specific approach has not been extensively tested in prior studies, making it a novel investigation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients over 18 years of age.
* Cancer patients, undergoing placement of CVCTI for chemotherapy, in follow-up, who finished chemotherapy up to a maximum period of 10 weeks.
* Eastern Cooperative Oncology Group (ECOG) status of 0 or 1
* Evidence of signed and dated informed consent indicating that the patient has been informed of all relevant aspects of the study and agrees to participate.

Exclusion Criteria:

* Presence of metastases or any other condition that may be an indication for intravenous treatments or additional chemotherapy regimens
* History of CVCTI-related adverse events during the treatment phase
* Patients on anticoagulant medication
* History of thrombophilia
* Pregnancy/Breastfeeding

Where this trial is running

Braga

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cancer, Central venous catheter

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.