Optimizing HIV prevention for people who inject drugs using a checklist

SIRI Checklist: An Integrated Hospital Model to Optimize HIV Prevention in Persons Who Inject Drugs

NA · University of Alabama at Birmingham · NCT05480956

This study is testing a new checklist to see if it can help improve HIV prevention and treatment for people who inject drugs in rural areas.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Alabama at Birmingham (other)
Locations1 site (Birmingham, Alabama)
Trial IDNCT05480956 on ClinicalTrials.gov

What this trial studies

This study aims to develop and test a SIRI checklist designed to enhance evidence-based treatment for rural individuals who use drugs. It will involve a prospective analysis of 60 hospitalized persons who inject drugs (PWUD) at UAB, assessing their HIV risk behaviors, substance use, and attitudes towards opioid use disorder treatment and HIV prevention. The study will utilize standardized surveys to gather data on infections, PrEP use, and barriers to care, ultimately aiming to improve hospital-based care models for addiction treatment and infection prevention.

Who should consider this trial

Good fit: Ideal candidates for this study are HIV-negative individuals aged 18 and older with opioid use disorder who are hospitalized at UAB.

Not a fit: Patients who are HIV positive or unable to provide informed consent due to acute illness or intoxication will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve HIV prevention and addiction treatment outcomes for rural populations who inject drugs.

How similar studies have performed: Other studies have shown success with similar integrated care approaches, suggesting potential for this model to be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* We will include 60 PWUD with serious injection related infections (SIRI) who are HIV negative, ≥ 18 years old, have opioid use disorder (OUD) and receiving care at UAB Hospital

Exclusion Criteria:

* We will exclude those unable to provide informed consent due to acute illness or intoxication, those who don't have OUD, and those who are HIV positive in order to inform HIV prevention interventions.

Where this trial is running

Birmingham, Alabama

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: HIV Infections, Opioid-Related Disorders, Pre-Exposure Prophylaxis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.