Clinical trial Recruiting at 1 site Observational Ages 18 to 80

Optimizing catheter ablation techniques for atrial fibrillation

Official title: Application Value of Whole-procedure Optimization for Catheter Ablation of Atrial Fibrillation

Run by Henan Provincial People's Hospital · NCT06145906 · Data updated 2026-11-12

This study is testing new ways to make catheter ablation for atrial fibrillation more successful and help patients stay free of AF longer.

Quick facts

Study typeObservational
Ages18 Years to 80 Years
SexAll
Enrollment400 (estimated)
SponsorHenan Provincial People's Hospital
Academic / other
Locations1 site (Zhengzhou, Henan)
StatusRecruiting
StartedDecember 26, 2023
Main results expectedDecember 1, 2026
Study endsDecember 1, 2026
Registry record updatedMarch 18, 2024
Trial IDNCT06145906 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients undergoing their first radiofrequency catheter ablation for atrial fibrillation.

Probably not a fit

Patients with a history of AF radiofrequency ablation, significant left atrial enlargement, or other serious cardiac conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to enhance the success rate of catheter ablation for atrial fibrillation (AF) by implementing optimized strategies and workflows. It focuses on improving the durability of conduction block during the procedure, which is crucial for long-term AF-free survival. The study will involve first-time radiofrequency catheter ablation patients and will assess various interventions, including pulmonary vein isolation and linear ablation techniques. By addressing the challenges of creating effective lesions, the study seeks to reduce the recurrence of AF post-procedure.

Why it matters

Potential benefit: If successful, this study could significantly improve the long-term outcomes for patients undergoing catheter ablation for atrial fibrillation.

How similar studies have gone: While catheter ablation techniques have been studied extensively, this specific optimization approach is novel and has not been widely tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Radiofrequency catheter ablation for the first time
* AF rhythm recorded by ECG

Exclusion Criteria:

* Thrombosis in left atrium
* Left ventricular ejection fraction of \< 35%
* Abnormal thyroid function
* Previous history of AF radiofrequency ablation and CABG
* Left atrium diameter of \> 65 mm or the volume of \> 200 ml

Where it's running

  • Department of Cardiology, Henan Provincial People's Hospital
    Zhengzhou, Henan, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.