Optimizing catheter ablation techniques for atrial fibrillation
Application Value of Whole-procedure Optimization for Catheter Ablation of Atrial Fibrillation
This study is testing new ways to make catheter ablation for atrial fibrillation more successful and help patients stay free of AF longer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Henan Provincial People's Hospital Academic / other |
| Locations | 1 site (Zhengzhou, Henan) |
| Trial ID | NCT06145906 on ClinicalTrials.gov |
What this trial studies
This observational study aims to enhance the success rate of catheter ablation for atrial fibrillation (AF) by implementing optimized strategies and workflows. It focuses on improving the durability of conduction block during the procedure, which is crucial for long-term AF-free survival. The study will involve first-time radiofrequency catheter ablation patients and will assess various interventions, including pulmonary vein isolation and linear ablation techniques. By addressing the challenges of creating effective lesions, the study seeks to reduce the recurrence of AF post-procedure.
Who should consider this trial
Good fit: Ideal candidates for this study are patients undergoing their first radiofrequency catheter ablation for atrial fibrillation.
Not a fit: Patients with a history of AF radiofrequency ablation, significant left atrial enlargement, or other serious cardiac conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve the long-term outcomes for patients undergoing catheter ablation for atrial fibrillation.
How similar studies have performed: While catheter ablation techniques have been studied extensively, this specific optimization approach is novel and has not been widely tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Radiofrequency catheter ablation for the first time * AF rhythm recorded by ECG Exclusion Criteria: * Thrombosis in left atrium * Left ventricular ejection fraction of \< 35% * Abnormal thyroid function * Previous history of AF radiofrequency ablation and CABG * Left atrium diameter of \> 65 mm or the volume of \> 200 ml
Where this trial is running
Zhengzhou, Henan
- Department of Cardiology, Henan Provincial People's Hospital — Zhengzhou, Henan, China (Recruiting)
Study contacts
- Study coordinator: Yingjie Chu
- Email: hnqbdsl@126.com
- Phone: +8613027736160
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.