Optimizing catheter ablation techniques for atrial fibrillation
Official title: Application Value of Whole-procedure Optimization for Catheter Ablation of Atrial Fibrillation
Run by Henan Provincial People's Hospital · NCT06145906 · Data updated 2026-11-12
This study is testing new ways to make catheter ablation for atrial fibrillation more successful and help patients stay free of AF longer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Henan Provincial People's Hospital Academic / other |
| Locations | 1 site (Zhengzhou, Henan) |
| Status | Recruiting |
| Started | December 26, 2023 |
| Main results expected | December 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | March 18, 2024 |
| Trial ID | NCT06145906 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients undergoing their first radiofrequency catheter ablation for atrial fibrillation.
✕Probably not a fit
Patients with a history of AF radiofrequency ablation, significant left atrial enlargement, or other serious cardiac conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to enhance the success rate of catheter ablation for atrial fibrillation (AF) by implementing optimized strategies and workflows. It focuses on improving the durability of conduction block during the procedure, which is crucial for long-term AF-free survival. The study will involve first-time radiofrequency catheter ablation patients and will assess various interventions, including pulmonary vein isolation and linear ablation techniques. By addressing the challenges of creating effective lesions, the study seeks to reduce the recurrence of AF post-procedure.
Why it matters
Potential benefit: If successful, this study could significantly improve the long-term outcomes for patients undergoing catheter ablation for atrial fibrillation.
How similar studies have gone: While catheter ablation techniques have been studied extensively, this specific optimization approach is novel and has not been widely tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Radiofrequency catheter ablation for the first time * AF rhythm recorded by ECG Exclusion Criteria: * Thrombosis in left atrium * Left ventricular ejection fraction of \< 35% * Abnormal thyroid function * Previous history of AF radiofrequency ablation and CABG * Left atrium diameter of \> 65 mm or the volume of \> 200 ml
Where it's running
-
Department of Cardiology, Henan Provincial People's Hospital
Zhengzhou, Henan, China Recruiting
Study contacts
- Study coordinator: Yingjie Chu
- Email: hnqbdsl@126.com
- Phone: +8613027736160
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.