Opioid-free care for patients undergoing obesity surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of an opioid-free care pathway compared to traditional opioid-based treatment for pain relief in patients undergoing obesity surgery. It aims to assess pain management, recovery quality, and opioid consumption through a randomized, non-blinded, multi-centre approach. The study will utilize various interventions, including dexmedetomidine and person-centred care, to explore their impact on postoperative outcomes. The research is approved by relevant authorities and spans from November 2018 to December 2022.

Why it matters

Who can join: the full rules

Inclusion Criteria:

-Patients ≥18 years planned to undergo laparoscopic obesity surgery (GBP alt Sleeve surgery) at the selected site.

Exclusion Criteria:

* ASA\> III
* Cardiovascular disease with bradycardia (\<50 bpm)
* Serious liver disease failure
* Insufficient knowledge of the Swedish language
* Serious untreated psychiatric disease
* Neurocognitive dysfunction
* Pregnancy
* Women of childbearing age without contraception
* Malignant disease with expected short survival
* Patients treated with opioids for chronic pain
* Substance abuse
* Hypersensitivity to Oxycodone, Esketamine, Dexmedetomidine, and Lidocaine
* Pacemaker or ICD
* Inability to fill in questionnaires
* Decline participation,

Where it's running

• Lindesberg Hospital
  Lindesberg, Region Örebro, Sweden Recruiting
• Sahlgrenska University hospital/ Östra hopsital
  Gothenburg, Vg, Sweden Recruiting

Study contacts

• Principal investigator: Sven-Egron Thörn, MD, PhD — Göteborg University
• Study coordinator: Axel Wolf, RN, PhD
• Email: axel.wolf@gu.se
• Phone: +46709355364

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.