Online program to reduce vaping and future cigarette risk in young adults

Development of An Online, Theory-Based Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults: A Pilot Study

Not applicable Interventional University of Southern California · NCT06129123

This study tests a brief 30-minute online program to help 18–24 year-olds who vape cut back on e-cigarette use and lower their chance of trying cigarettes over 8 weeks.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 24 Years
SexAll
SponsorUniversity of Southern California Academic / other
Locations1 site (Los Angeles, California)
Trial IDNCT06129123 on ClinicalTrials.gov

What this trial studies

Researchers will randomize young adult e-cigarette users to either a 30-minute mobile-based intervention or an assessment-only control, with the control group offered access after the final survey. All participants complete online surveys at baseline and at 2, 4, and 8 weeks to measure past 7-day vaping frequency and susceptibility to smoking. The trial compares changes in vaping behavior and smoking susceptibility between groups over an 8-week period. The primary goal of this pilot is to determine whether the brief online intervention produces greater short-term reductions than control.

Who should consider this trial

Good fit: Ideal candidates are English-speaking 18–24 year-olds who currently vape at least one day per week, have no history of cigarette use, and are not receiving nicotine cessation services.

Not a fit: People with a history of cigarette use, severe mental health or substance use disorders, those currently receiving nicotine cessation treatment, non-English speakers, or those outside the eligible age range are unlikely to qualify or benefit from this intervention.

Why it matters

Potential benefit: If successful, the program could help young adults reduce how much they vape and decrease their risk of starting to smoke cigarettes.

How similar studies have performed: Brief digital interventions for tobacco use have shown modest success, but online programs specifically targeting young adult e-cigarette use remain relatively novel with limited prior evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* be between the ages of 18 to 24
* be able to read English
* report vaping at least one day per week in the past month
* report no history of cigarette use at screening and baseline.

Exclusion Criteria:

* reporting severe mental health, illicit drug use, or alcohol use disorder
* currently receiving nicotine cessation services

Where this trial is running

Los Angeles, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions E-cigarette Use
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.