Online nutritional coaching for overweight patients with obesity and high cardiometabolic risk

Efficacy of Telenutrition (OBE-COACH) for the Treatment of Overweight Patients With Obesity and/or High Cardiometabolic Risk

NA · Assistance Publique - Hôpitaux de Paris · NCT04941651

This study tests whether an online nutritional coaching program can help overweight people with obesity and high heart health risks lose weight and improve their health compared to a regular e-learning program.

Quick facts

PhaseNA
Study typeInterventional
Enrollment346 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorAssistance Publique - Hôpitaux de Paris (other)
Locations1 site (Paris)
Trial IDNCT04941651 on ClinicalTrials.gov

What this trial studies

The OBE-COACH program is an automated online nutritional coaching service designed to improve lifestyle habits in overweight patients with obesity and/or high cardiometabolic risk. Participants will be enrolled in a controlled study where one group receives access to the OBE-COACH program, while the control group utilizes an e-learning program without the interactive coaching. The study will assess participants at baseline, 6 months, and 12 months to evaluate the program's effectiveness in promoting weight loss and improving health outcomes. The program aims to enhance long-term adherence to dietary and physical activity recommendations.

Who should consider this trial

Good fit: Ideal candidates are men and women aged 18 to 75 with obesity or overweight and at least one cardiometabolic risk factor.

Not a fit: Patients with uncontrolled psychiatric illnesses or recent cardiovascular events may not benefit from this program.

Why it matters

Potential benefit: If successful, this program could significantly improve weight management and reduce cardiometabolic risks for patients.

How similar studies have performed: Previous studies have shown success with similar online nutritional coaching approaches, indicating potential for this enhanced program.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Men or women 18 to 75 years
* Obesity defined by a body mass index \> 30 kg / m2 or a BMI\> 25 kg / m2 with the presence of at least one major cardiometabolic risk factors among the followings: dyslipidemia, hypertension, diabetes, prediabetes
* Stable weight in the last six months (weight variation \< 4 kg peak-to-peak)
* Access and current use of internet, possession of an email address and a smartphone.
* Understanding and reading French
* Patient not currently following a nutritional monitoring and not having planned to be engaged in a nutritional monitoring during the coming year

Exclusion Criteria:

* Excessive alcohol consumption \> 30 g / day -Pregnant or breastfeeding woman
* symptomatic cardiovascular disease : angina, lower extremity arterial occlusive disease, stroke or myocardial infarction dating of less than 6 months.
* Uncontrolled psychiatric illness
* Patients receiving or about to receive during the study period a systemic or local treatment susceptible to interfere with the evaluation of the primary criteria (corticosteroids, antipsychotics, tricyclic antidepressants) except if these treatments have been stable for at least 6 months without a plan to modify the dose during the 12 months of the study
* Adhering to a prescribed diet for weight loss, in the past 3 months
* Person with a severe eating disorder: bulimia, binge eating disorder according to DSM-V criteria - Presence of celiac disease, Crohn's disease or other metabolic disorder or condition affecting nutritional needs such as allergies or food intolerances (except partial lactose intolerance)
* Anticipated difficulties in following the patient
* Lack of social coverage in France
* Lack of written or electronic informed consent

Where this trial is running

Paris

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Overweight and Obesity, Overweight patients, Obesity, Cardiometabolic risk, telenutrition, online nutritional coaching service

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.