Online Hatha Yoga Add-On for High-Frequency Episodic Migraine
Official title: A Randomized Controlled Trial of an Online Hatha Yoga Program as an Add-On Therapy for Episodic High-Frequency Migraine
Run by University of Seville · NCT07694063 · Data updated 2026-11-12
This trial tests whether a 12-week online Hatha yoga program added to usual migraine treatment can help adults with high-frequency episodic migraine.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University of Seville Academic / other |
| Locations | 1 site (Seville, Sevilla) |
| Status | Recruiting |
| Started | January 27, 2026 |
| Main results expected | October 30, 2026 |
| Study ends | October 30, 2026 |
| Registry record updated | July 9, 2026 |
| Trial ID | NCT07694063 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18-65 with a neurologist-confirmed diagnosis of high-frequency episodic migraine, on stable migraine medications, and able to participate in online exercise.
✕Probably not a fit
Individuals with chronic migraine (≥15 headache days/month), significant neurological or psychiatric conditions, or without reliable internet access or Spanish language proficiency may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this randomized, parallel-group study, adults with high-frequency episodic migraine will either receive a 12-week home-based online Hatha yoga program in addition to their usual preventive medication or continue with usual care alone. The primary outcomes are migraine frequency, pain intensity, and functional impact, measured before and after the intervention. Secondary outcomes include sleep quality, anxiety/depression symptoms, physical activity, global impression of change, and adherence to the program. Assessments occur at baseline and after 14 weeks, and participants are recruited from a hospital headache unit and a local primary care center in Seville, Spain.
Why it matters
Potential benefit: If successful, the program could provide a feasible, non-pharmacological option to reduce migraine burden for those with high-frequency episodic migraine.
How similar studies have gone: Previous trials have shown activity-based or yoga interventions can improve headache-related outcomes, but online add-on approaches for this specific population are still being established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria * Adults aged 18-65 years * Diagnosis of episodic high-frequency migraine according to ICHD criteria * Diagnosis confirmed by a neurologist * At least 1-year history of migraine * Receiving stable pharmacological treatment for ≥3 months before enrollment * Willing to maintain stable medication during the study * Ability to understand study procedures and complete assessments * Signed informed consent * Willingness to be randomized Exclusion Criteria * Other significant neurological disorders * Severe psychiatric conditions affecting participation * Medical contraindications to moderate physical activity * Chronic migraine (≥15 headache days/month) * Use of more than one preventive migraine medication * Lack of Spanish language comprehension * Lack of internet access or digital skills for online intervention
Where it's running
-
University Hospital Virgen del Rocio
Seville, Sevilla, Spain Recruiting
Study contacts
- Principal investigator: Cristina García Muñoz, PhD — University of Seville
- Study coordinator: Cristina García Muñoz, PhD, PT
- Email: ccriss.g@gmail.com
- Phone: +34954551468
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.