Online group therapy for postpartum depression led by nurses and peers

Public Health Nurse-Peer Co-Delivered Group Cognitive Behavioral Therapy for Postpartum Depression: a Randomized Controlled Trial

Not applicable Interventional McMaster University · NCT06597448

This study is testing whether a 9-week online group therapy program for postpartum depression, led by nurses and trained peers, can help new mothers feel better compared to just getting standard treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment170 (estimated)
Ages18 Years and up
SexFemale
SponsorMcMaster University Academic / other
Locations1 site (Hamilton, Ontario)
Trial IDNCT06597448 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a 9-week online group Cognitive Behavioral Therapy (CBT) intervention for postpartum depression (PPD), co-led by public health nurses and trained peers who have recovered from PPD. The trial involves 170 mothers or birthing parents, half of whom will receive the intervention in addition to standard treatment, while the other half will receive standard treatment alone. Participants will complete online questionnaires at three different time points to assess the intervention's impact on PPD, anxiety, and related complications. The study also aims to determine the cost-effectiveness of this approach.

Who should consider this trial

Good fit: Ideal candidates are mothers or birthing parents aged 18 and older with infants under 12 months who have a moderate to severe score on the Edinburgh Postnatal Depression Scale.

Not a fit: Patients with bipolar disorder, psychotic disorders, current substance use disorders, or borderline personality disorder may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the mental health and well-being of mothers experiencing postpartum depression.

How similar studies have performed: Previous studies have shown that peer-led interventions can be effective for mental health conditions, suggesting potential success for this novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Mothers or birthing parents, 18 years old, have an infant under 12 months of age at recruitment, fluent in written/spoken English, have a Edinburgh Postnatal Depression Scale (EPDS) score ≥10 and live in Ontario, Canada.

Exclusion Criteria:

Bipolar, psychotic, or current substance use disorders and borderline personality disorder as assessed during screening when study coordinator administers the Mini International Neuropsychiatric Interview (MINI).

Where this trial is running

Hamilton, Ontario

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postpartum DepressionPostpartum depression, PPDCognitive Behavioural TherapyPublic Health NursePeer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.