Online exercise program for adults with gastric cancer during treatment
Online Exercise Program During Perioperative Treatment in Adults With Gastric Cancer (On4Cancer): Randomized Controlled Trial
This study tests whether an online exercise program can help adults with gastric cancer feel better and improve their fitness while they are undergoing chemotherapy before surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Maia Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Vila Nova De Gaia) |
| Trial ID | NCT06254300 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of an online, supervised exercise-based prehabilitation program on cardiorespiratory fitness, functional fitness, and quality of life in adults with gastric cancer undergoing neoadjuvant chemotherapy. Participants will engage in a structured exercise regimen while receiving standard perioperative chemotherapy with the FLOT4 regimen. The goal is to improve physical fitness and mitigate the negative impacts of treatment-related toxicities. The program is designed for individuals diagnosed with resectable gastric cancer who are preparing for surgical intervention.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with stage II/III gastric cancer who are scheduled for surgical treatment and willing to participate in an online exercise program.
Not a fit: Patients with distant metastatic disease or those unable to engage in physical training will not benefit from this study.
Why it matters
Potential benefit: If successful, this program could enhance physical fitness and improve postoperative outcomes for patients with gastric cancer.
How similar studies have performed: Previous studies have shown that exercise-based prehabilitation can improve outcomes in cancer patients, suggesting a positive outlook for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years. * Willingness to participate in the study. * Referral for surgical treatment for gastric cancer. * Diagnosis of gastric cancer for curative intent - stage II/III * Referall to the perioperative FLOT4 chemotherapy regimen * ECOG PS 0-1. * Receptiveness and availability to use the proposed technology for exercise sessions Exclusion Criteria: * Inability to provide informed consent * Inability to engage in physical training or perform the baseline walking test * Presence of distant metastatic disease * History of previous or concurrent malignancy * Diagnosis of heart failure, ischemic heart disease, or sinus node valvular disease * Pregnancy.
Where this trial is running
Vila Nova De Gaia
- Centro Hospitalar de Vila Nova de Gaia/Espinho — Vila Nova De Gaia, Portugal (Recruiting)
Study contacts
- Study coordinator: Lia F Bahut, MSc
- Email: lia.bahut@gmail.com
- Phone: +351 22 986 6000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.