Online cognitive behavior therapy for common mental disorders in primary care
Internet-based Transdiagnostic Cognitive Behavior Therapy and Care As Usual for Primary Care Patients with Mental Ill-health (RCT-1:Common Mental Disorders)
This study is testing whether online cognitive behavior therapy can help adults with common mental health issues feel better compared to regular care they usually receive.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 1 site (Gustavsberg, Stockholm County) |
| Trial ID | NCT06804941 on ClinicalTrials.gov |
What this trial studies
This randomized controlled trial aims to evaluate the effectiveness of online transdiagnostic cognitive behavior therapy (CBT) compared to standard care for adult primary care patients with common mental disorders. Participants will be randomly assigned to receive either online CBT, which includes psychoeducation and therapeutic exercises delivered through a secure web platform, or care as usual. The study will assess symptomatic improvement, quality of life, and functional impairment, while also exploring treatment moderators and mediators. The goal is to provide evidence for a more accessible and resource-efficient treatment option for common mental disorders.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a diagnosed common mental disorder who can read and write in Swedish and have regular internet access.
Not a fit: Patients with severe psychiatric disorders requiring specialized care, such as psychosis or bipolar disorder, will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve access to effective mental health treatment for patients in primary care settings.
How similar studies have performed: Other studies have shown promise for online CBT approaches, but this specific transdiagnostic method in a primary care context is still being evaluated.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: To be included patients have to: 1. have a common mental disorder in form of an anxiety disorder (social phobia, panic disorder, agoraphobia, general anxiety disorder, or specific phobia), health anxiety (hypochondriasis or illness anxiety disorder), obsessive-compulsive disorder, depression (depression or dysthymia), or a stress-related disorder (exhaustion disorder, adjustment disorder, or post-traumatic stress disorder), that warrants treatment, 2. be at least 18 years old, 3. have regular access to a device with an Internet connection, 4. be able to read and write in Swedish, 5. have no severe psychiatric disorder that requires specialized psychiatric care, such as psychosis, bipolar disorder, or anorexia nervosa, 6. if on medication with monoamine agonist, have stable dosage in the past month, 7. have no on-going psychological treatment, and 8. provide written informed consent for participation and complete baseline assessment
Where this trial is running
Gustavsberg, Stockholm County
- Region Stockholm, Gustavsberg Primary Care Center — Gustavsberg, Stockholm County, Sweden (Recruiting)
Study contacts
- Principal investigator: Erik Hedman-Lagerlöf, PhD, professor — Region Stockholm and Karolinska Institutet
- Study coordinator: Mari von Bahr Bentzer, MSc.
- Email: mari.vonbahr-bentzer@regionstockholm.se
- Phone: +46 8 123 395 50
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.