One-Finger Technique to identify the left upper ureter during para-aortic lymphadenectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-arm study evaluates the feasibility and safety of the One-Finger Technique for identifying the left upper ureter during open para-aortic lymphadenectomy in patients with ovarian, endometrial, or cervical cancer. Eligible participants are women 18–75 undergoing open surgery with para-aortic lymphadenectomy planned. The study focuses on whether the technique can be performed safely and effectively in real surgical settings. Outcomes include feasibility and safety measures, such as identification success and intraoperative complications. It does not have a control group.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Females aged 18-75 years;
* Diagnosed with gynecological malignancies (e.g., cervical cancer, endometrial cancer, ovarian cancer) confirmed by histopathology or cytology;
* Planned to receive open surgical treatment and have surgical indications for para-aortic lymphadenectomy according to guidelines;
* ECOG performance status score: 0\~1;
* Fully understand the purpose, nature, methods, and potential risks and benefits of this study, voluntarily participate in this study, and sign a written informed consent form.

Exclusion Criteria:

* Concurrently have malignant tumors in other systems;
* Previous history of left kidney or ureter surgery, or known severe anatomical variations of the urinary system (such as duplex kidney, duplex ureter, pelvic ectopic kidney, etc.);
* Severe intestinal adhesions caused by previous abdominal surgery for other reasons;
* Previous history of pelvic/abdominal radiotherapy, or severe adhesions and unclear anatomical structures in the retroperitoneal space due to previous abdominal surgery or severe pelvic/abdominal infection;
* Preoperative imaging (CT/MRI) indicates massive confluent lymph nodes in the retroperitoneum, or lymph nodes that have encased major blood vessels such as the left ureter, abdominal aorta, and inferior vena cava, where routine space dissection is expected to be impossible;
* Presence of absolute contraindications for open surgery, such as severe cardiac, hepatic, or renal insufficiency, or coagulopathy;
* Other conditions deemed unsuitable for enrollment by the investigator.

Where it's running

• Sun Yat-sen Memorial Hospital, Sun Yat-sen University
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Principal investigator: Jing Li, MD — Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
• Study coordinator: Dongyan Wang, MD
• Email: wangdy35@mail.sysu.edu.cn
• Phone: +86 15017554658

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.