Omega-3 Fatty Acids and Red Blood Cell Membranes in Competitive Soccer Players

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, placebo-controlled trial evaluates the impact of four weeks of high-dose EPA and DHA on erythrocyte membrane composition, the Omega-3 Index, and a range of physiological and cognitive outcomes in male competitive soccer players. Participants continue their usual training and diet, with no lifestyle changes mandated. Primary measurements include the erythrocyte fatty acid profile and Omega-3 Index, while secondary outcomes cover cognitive function, hormonal status, speed, endurance, hematological and lipid parameters, inflammatory markers, and oxidative status. The study aims to clarify whether short-term omega-3 supplementation can modulate muscle-related factors and cognitive performance in this athletic population.

Why it matters

Who can join: the full rules

\*\*Inclusion Criteria:\*\*

* Male competitive soccer players aged 16-35 years.
* Regular participation in organized soccer training and competition.
* A minimum of 6 years of systematic soccer training experience.
* Participation in regular team training during the study period.
* Habitual mixed diet.
* Ability and willingness to maintain usual dietary habits and training load throughout the 4-week intervention.
* Written informed consent provided by the participant.
* For participants under 18 years of age, written informed consent provided by a parent or legal guardian and assent provided by the participant.

\*\*Exclusion Criteria:\*\*

* Current use of omega-3 fatty acid supplements or fish-oil products.
* Use of omega-3 supplements within the 3 months preceding enrollment.
* Known allergy or hypersensitivity to fish, seafood, fish oil, or any ingredient of the study supplements.
* Diagnosed cardiovascular, metabolic, endocrine, gastrointestinal, neurological, inflammatory, autoimmune, or hematological disease.
* Acute infection, injury, or illness that could affect participation in training or study assessments.
* Use of medications or dietary supplements that could influence lipid metabolism, inflammatory status, hormonal profile, blood coagulation, cognitive function, or physical performance.
* Regular use of anticoagulant or antiplatelet medication.
* Significant change in diet, training volume, or supplementation during the study period.
* Failure to comply with the supplementation protocol or attendance requirements.
* Participation in another clinical or nutritional intervention study during the study period.

Where it's running

• Jerzy Kukuczka Academy of Physical Education in Katowice
  Katowice, Mikolowska 72a, Poland Recruiting

Study contacts

• Study coordinator: Małgorzata Magdalena Michalczyk, Professor
• Email: m.michalczyk@awf.katowice.pl
• Phone: +48535016532

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.