Off-clamp, sutureless robot-assisted partial nephrectomy for small kidney tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional protocol uses a robot-assisted partial nephrectomy technique that omits renal artery clamping and replaces traditional renorrhaphy with haemostatic, sutureless measures. Eligible adults with single renal tumors ≤7 cm and no collecting system invasion receive the off-clamp sutureless approach and are followed for perioperative outcomes and renal function changes. Key outcomes include intraoperative blood loss, operative time, conversions to open or radical surgery, postoperative complications, and changes in estimated glomerular filtration rate (eGFR). Patients with distant metastasis, multiple unresectable lesions, prior systemic therapy, or intraoperative conversion are excluded from analysis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age between 18 and 80 years old, regardless of gender;
2. Radiological findings demonstrating a tumor size of ≤7 cm;
3. Imaging studies showing no evidence of collecting system invasion;
4. Scheduled to undergo robot-assisted partial nephrectomy (RAPN).

Exclusion Criteria:

1. Preoperative imaging demonstrating evidence of distant metastasis or lymph node involvement;
2. Unilateral or bilateral multiple lesions not amenable to simultaneous resection;
3. History of prior systemic therapy, including molecular targeted therapy, immunotherapy, or chemotherapy;
4. Intraoperative conversion to radical nephrectomy;
5. Intraoperative conversion to open surgery.

Where it's running

• The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Principal investigator: Pengfei Shao, Professor — The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital), Nanjing, Jiangsu 210036
• Study coordinator: Pengfei Shao, Professor
• Email: spf032@hotmail.com
• Phone: +8613851925825

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.