Observing the relationship between interstitial lung disease and obstructive sleep apnea
Official title: Study on the Clinical Characteristics of Interstitial Lung Disease and Obstructive Sleep Apnea
Run by Tianjin Medical University General Hospital · NCT05838183 · Data updated 2026-11-12
This study looks at how interstitial lung disease and obstructive sleep apnea affect each other in patients to find out more about their symptoms and possible causes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Tianjin Medical University General Hospital Academic / other |
| Locations | 1 site (Tianjin) |
| Status | Recruiting |
| Started | September 1, 2019 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | February 10, 2026 |
| Trial ID | NCT05838183 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 to 80 with a clinical diagnosis of interstitial lung disease or obstructive sleep apnea.
✕Probably not a fit
Patients with malignant tumors, severe heart failure, uremia, autoimmune diseases, pulmonary embolism, end-stage chronic obstructive pulmonary disease, or those unable to provide informed consent due to mental illness may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study collects clinical data from patients diagnosed with interstitial lung disease (ILD) and obstructive sleep apnea (OSA). It involves the collection of bronchoscopic specimens and utilizes rapid on-site evaluation (ROSE) alongside metagenomic next-generation sequencing (mNGS) to explore the biological characteristics and causes of exacerbations in these patients. Additionally, all participants will undergo polysomnography and drug-induced sleep endoscopy to assess their conditions further. The study aims to identify specific biomarkers that can differentiate between various patient groups.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic methods and treatment strategies for patients suffering from both ILD and OSA.
How similar studies have gone: While the specific combination of ILD and OSA in this context may be novel, similar studies exploring the relationship between respiratory conditions and sleep disorders have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * over 18 years old and under 80 years old. * Clinical diagnosis of interstitial lung disease or obstructive respiratory sleep apnea syndrome. * Patient is conscious and capable of signing informed consent. * The patient may wear a polysomnograph. Exclusion criteria: * malignant tumors. * severe heart failure. * uremia. * autoimmune diseases. * pulmonary embolism, and end-stage chronic obstructive pulmonary disease. * Patients with mental illnesscannot sign informed consent on their own.
Where it's running
-
Tianjin Medical University General Hospital
Tianjin, China Recruiting
Study contacts
- Study coordinator: Dan Liu
- Email: liudan_nkdx@163.com
- Phone: 13920701949
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.