Clinical trial Recruiting at 1 site Observational Ages 18 and up

Observing the natural progression of interstitial lung disease

Official title: A Study of the Natural Progression of Interstitial Lung Disease (ILD)

Run by University of Chicago · NCT00470327 · Data updated 2026-11-12

This study is collecting data and blood samples from people with interstitial lung disease to see how the condition progresses over time and to better understand its effects.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment4000 (estimated)
SponsorUniversity of Chicago
Academic / other
Locations1 site (Chicago, Illinois)
StatusRecruiting
StartedSeptember 2005
Main results expectedDecember 2030
Study endsDecember 2030
Registry record updatedJune 9, 2026
Trial IDNCT00470327 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals diagnosed with interstitial lung disease.

Probably not a fit

Patients who do not have interstitial lung disease will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to collect data and blood samples from patients diagnosed with interstitial lung disease (ILD) as well as a control group for comparison. By analyzing these samples, researchers hope to describe the phenotypic expression of various forms of ILD, including idiopathic pulmonary fibrosis and sarcoidosis. The observational nature of the study allows for a comprehensive understanding of disease progression without any specific interventions. This data will contribute to a better understanding of ILD and its impact on patients.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of interstitial lung diseases, leading to improved diagnosis and treatment strategies for patients.

How similar studies have gone: Other studies focusing on the natural progression of interstitial lung diseases have shown promise in understanding these conditions, making this approach both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Interstitial lung disease

Exclusion Criteria:

* Does not have Interstitial lung disease

Where it's running

  • University of Chicago
    Chicago, Illinois, United States
    Recruiting

Study contacts

  • Principal investigator: Mary E Strek, MD — University of Chicago
  • Study coordinator: Vanita Patel, MPH
  • Phone: 773-702-1012

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Photon-counting CT vs standard HRCT to help diagnose IPF and other ILDs

    This study tests whether photon-counting CT can improve identifying IPF and other ILDs compared with standard HRCT for patients discussed in multidisciplinary teams.

    Recruiting Istituto Clinico Humanitas · Rozzano, Italy · NCT07790614

  • Biobank for interstitial lung diseases

    This study is setting up a collection of health information and samples from patients with interstitial lung diseases to help researchers learn more about the condition and find better treatments.

    Recruiting University of Kansas Medical Center · Kansas City, Kansas · NCT05392881

  • New IPF drug ORJ-001 tested in adults with IPF

    A phase 2 study tests ORJ-001 versus placebo in adults with idiopathic pulmonary fibrosis to see if it is tolerated and whether it helps lung function.

    Recruiting at 2 sites Phase 2 Oorja Bio, Inc. · Doral, Florida and 1 other locations · NCT07869147

  • Nalbuphine ER for IPF-related chronic cough

    This study tests whether extended-release nalbuphine tablets can reduce chronic cough in people with idiopathic pulmonary fibrosis.

    Recruiting at 4 sites Phase 3 Trevi Therapeutics · Wilmington, Delaware and 3 other locations · NCT07868419

  • Home-based pulmonary rehabilitation for interstitial lung disease

    This study tests a 6-week home-based pulmonary rehabilitation program to see if it improves breathing, exercise ability, and quality of life for people with fibrotic interstitial lung disease in India.

    Recruiting Post Graduate Institute of Medical Education and Research, Chandigarh · Chandigarh, Chandigarh · NCT07830602

  • Inspiratory Flow Rate Capability in Pulmonary Fibrosis Patients

    This observational study tests how fast patients with IPF or PPF can inhale through dry powder inhalers with different resistances.

    Recruiting Shanghai Pulmonary Hospital, Shanghai, China · Shanghai, Shanghai Municipality · NCT07820254

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.