Observing the impact of treatment strategies on critically ill patients in the ICU

Burden, Mortality and Supply Costs in Intensive Care Unit Patients. Health Services Research.

Observational University of Ulm · NCT04094428

This study looks at how different treatment approaches in the ICU affect the health and outcomes of critically ill patients based on their level of illness and frailty.

Quick facts

Study typeObservational
Enrollment700 (estimated)
SexAll
SponsorUniversity of Ulm Academic / other
Locations1 site (Ulm)
Trial IDNCT04094428 on ClinicalTrials.gov

What this trial studies

This observational study systematically examines the relationship between different therapy strategies (maximal therapy, withholding, and withdrawing treatment) and their outcomes in critically ill patients within the intensive care unit (ICU). It categorizes patients into three risk groups based on their clinical frailty and severity of disease, assessing endpoints related to burden of care, mortality, and supply costs. The study aims to provide insights into how these strategies affect patient outcomes in real-world settings.

Who should consider this trial

Good fit: Ideal candidates for this study are patients who are either dying in the ICU or have been admitted for at least 72 hours.

Not a fit: Patients who are not critically ill or those who do not meet the inclusion criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help optimize treatment strategies for critically ill patients, potentially improving their quality of care and resource allocation in the ICU.

How similar studies have performed: While similar observational studies have been conducted, this specific approach focusing on therapy strategies and their impact on burden, mortality, and costs in the ICU is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients dying on the ICU and all patients staying for at least 72 hours on the ICU

Exclusion Criteria:

* No

Where this trial is running

Ulm

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Burden, DependencyMortalityEnd-of-life CareIntensive Care UnitCritically Ill PatientFrailtyMultiple Organ Failureburden
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.