Observing the effectiveness of pacing therapy for congenital heart disease patients with atrial arrhythmias

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of atrial tachycardia pacing (ATP) therapy in patients with congenital heart disease (CHD) who have implanted atrial tachycardia devices (ATDs). The research will involve both retrospective and prospective data collection from a minimum of 250 subjects across multiple institutions. The study will focus on how well ATP works in managing atrial arrhythmias, particularly in patients who have undergone surgical interventions for CHD. No active interventions will be performed, as the study will primarily analyze existing patient data.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* must have structural CHD, an atrial arrhythmia and an ATD implanted. ATP must be turned on.

Exclusion Criteria:

* Other arrhythmias substrates such as Long QT (LQT), hypertrophic Cardiomyopathy (HCM), Catecholaminergic polymorphic ventricular tachycardia (CPVT), Arrhythmogenic Right Ventricular Cardiomyopathy.(ARVC), Brugada \& patients who undergo transplant, surgical maze, or ablation within 5 years of ATD implantation.

Where it's running

• Children's Hospital of Orange County (CHOC)
  Orange, California, United States Recruiting
• University of Iowa Children's Hospital
  Iowa City, Iowa, United States Recruiting
• Norton Healthcare
  Louisville, Kentucky, United States Recruiting
• University of Michigan
  Ann Arbor, Michigan, United States Recruiting
• Children's Hospital of Michigan
  Detroit, Michigan, United States Recruiting
• Baylor College of Medicine
  Houston, Texas, United States Recruiting

Study contacts

• Study coordinator: Ian Law, MD
• Email: ian-law@uiowa.edu
• Phone: 319-356-7303

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.