Observing severe sepsis and septic shock in surgical ICU patients

Severe Sepsis/Septic Shock on Admission to the General Surgical ICU

Mahidol University · NCT01363635

This study looks at how often severe sepsis and septic shock happen in adult surgical patients in the ICU to see how different treatments and factors affect their recovery.

Quick facts

Study typeObservational
Enrollment800 (estimated)
Ages19 Years to 90 Years
SexAll
SponsorMahidol University (other)
Locations1 site (Bangkoknoi, Bangkok)
Trial IDNCT01363635 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the incidence of severe sepsis and septic shock among adult surgical patients admitted to the general surgical ICU at Siriraj Hospital, Bangkok. It will collect data on various risk factors, resuscitation methods, and clinical outcomes, including organ failure and mortality rates. The study will involve 800 patients and focus on the effects of fluid replacement and other interventions within the first six hours of admission. By analyzing these factors, the study seeks to identify potential improvements in patient management and outcomes.

Who should consider this trial

Good fit: Ideal candidates are adult surgical patients over 18 years old who are admitted to the general surgical ICU.

Not a fit: Patients undergoing cardiothoracic, neurosurgery, or traumatic surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved survival rates and outcomes for patients experiencing severe sepsis and septic shock.

How similar studies have performed: Other studies have shown that early and aggressive resuscitation can improve outcomes in septic patients, suggesting that this approach may be beneficial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult (\> 18 years) surgical patient admitting to the general surgical ICU
* Consent to this study

Exclusion Criteria:

* Patient undergoing cardiothoracic surgery, neurosurgery and traumatic surgery
* Not consent to this study

Where this trial is running

Bangkoknoi, Bangkok

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Septic Shock, Multiple Organ Failure, Fatal Outcome, severe sepsis/septic shock, organ failure, AKI, PMI, ALI

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.