Observing severe infections caused by Group A Streptococcus in children
French Pediatric Nationwide Observatory of Invasive Group A Streptococcal Infection (in Childen for 0 to 18 Ages)
This study looks at children in the hospital with serious Group A Strep infections to see how common they are and what factors might make them worse.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 1 Day to 17 Years |
| Sex | All |
| Sponsor | Association Clinique Thérapeutique Infantile du val de Marne Academic / other |
| Locations | 1 site (Créteil) |
| Trial ID | NCT05788861 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on pediatric patients hospitalized with invasive Group A Streptococcal infections. It aims to identify and document cases of severe infections, evaluate their incidence, and analyze contributing factors to optimize management strategies. The study will compile epidemiological, clinical, and bacteriological data from both severe and non-severe cases to better understand the characteristics of these infections and their recent increase in occurrence. Patients admitted to intensive or critical care units may also be included in the analysis.
Who should consider this trial
Good fit: Ideal candidates for this study are pediatric patients under 18 years old with documented invasive Group A Streptococcus infections.
Not a fit: Patients who oppose participation or whose legal representatives do not consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management and treatment strategies for children suffering from severe Group A Streptococcal infections.
How similar studies have performed: While this study is observational, similar studies have shown success in understanding and managing severe infections, indicating potential for valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age\<18 years * Documented invasive Group A Streptococcus infection (identification of GAS in a normally sterile site or from another site in case of toxin shock or necrotizing dermo-hypodermatitis) Exclusion Criteria: * Opposition of the patient or his/her legal representative
Where this trial is running
Créteil
- Activ — Créteil, France (Recruiting)
Study contacts
- Principal investigator: Yves Gillet — hôpital Femme-Mère-Enfant, Bron
- Study coordinator: Levy Corinne
- Email: corinne.levy@activ-france.fr
- Phone: 1 48 85 04 04
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.