Observing kidney transplant patients to predict allograft survival and assess imaging impact
Prospective Monocentric Observational Study of Kidney Transplant Recipients at the CHU of Liege for the Prediction of Allograft Survival and Impact of Imaging in Clinical Decision-making.
This study is trying to find better ways to help kidney transplant patients by looking at different factors that might affect how long their transplant lasts and how stopping certain medications could impact their health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Liege Academic / other |
| Locations | 1 site (Liège) |
| Trial ID | NCT03764124 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on improving outcomes for kidney transplant recipients by developing personalized medicine approaches. It aims to integrate various data points, including donor and recipient characteristics, biopsy results, and imaging techniques like PET/CT, to predict individual risks of allograft loss. The study will also evaluate the effects of corticosteroid withdrawal on long-term outcomes and bone mineral density in these patients. By identifying early surrogate endpoints, the research seeks to aid clinical decision-making and therapeutic interventions.
Who should consider this trial
Good fit: Ideal candidates include kidney transplant recipients over 18 years of age who were transplanted after 2007 and have available clinical and follow-up data.
Not a fit: Patients who have undergone combined transplantation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better prediction of kidney allograft survival and improved management of transplant patients.
How similar studies have performed: Other studies have explored similar imaging techniques and risk prediction models in transplant settings, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Kidney recipient transplanted after 2007 * Kidney recipient over 18 years of age * Clinical, biological, immunological and follow up data available Exclusion Criteria: * Combined transplantation
Where this trial is running
Liège
- Centre Hospitalier Universitaire de Liège — Liège, Belgium (Recruiting)
Study contacts
- Principal investigator: FRANCOIS JOURET, PhD — CHU Liege department of Nephrology-Dialysis and Transplantation, and Groupe Interdisciplinaire de Géno-protéomique Appliquée, Cardiovascular Sciences.
- Study coordinator: Antoine Bouquegneau, MD
- Email: antoine.bouquegneau@gmail.com
- Phone: 0032473353321
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.