Clinical trial Recruiting at 1 site Observational

Observing complications and responses in cancer patients treated with anti-VEGF therapies

Official title: A Prospective Study Evaluating Complications and Clinical Response in Cancer Patients Treated With Anti-VEGF-Related Therapies

Run by M.D. Anderson Cancer Center · NCT05108519 · Data updated 2026-11-12

This study looks at how cancer patients treated with anti-VEGF therapies respond to the treatment and what complications they might face.

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Quick facts

Study typeObservational
SexAll
Enrollment170 (estimated)
SponsorM.D. Anderson Cancer Center
Academic / other
Locations1 site (Houston, Texas)
StatusRecruiting
StartedApril 8, 2019
Main results expectedFebruary 2, 2027
Study endsFebruary 2, 2027
Registry record updatedAugust 10, 2026
Trial IDNCT05108519 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are cancer patients currently receiving anti-VEGF-related therapies, either alone or in combination.

Probably not a fit

Patients not receiving anti-VEGF therapies or those unable to provide informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects data on complications and clinical responses in cancer patients undergoing treatment with anti-VEGF-related therapies at Emory University and the University of Texas M.D. Anderson Cancer Center. The primary objective is to explore the incidence of clinical complications associated with these therapies. Secondary objectives include examining the correlation between clinical response rates and a novel blood pressure scoring system, as well as the relationship between toxicity grades and treatment responses. Patient medical records will be reviewed to gather relevant information.

Why it matters

Potential benefit: If successful, this study could enhance understanding of the side effects of anti-VEGF therapies and improve treatment strategies for cancer patients.

How similar studies have gone: Other studies have explored the effects of anti-VEGF therapies, but this specific observational approach focusing on complications and a novel scoring system is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients must be able to understand and be willing to sign a written informed consent document
* Patients must be receiving any anti-VEGF-related regimen in monotherapy or combination therapy

Where it's running

  • M D Anderson Cancer Center
    Houston, Texas, United States
    Recruiting

Study contacts

  • Principal investigator: Nicolas L Palaskas — M.D. Anderson Cancer Center

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.