Observing changes in the eye's drainage angle after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with glaucoma who are undergoing various minimally invasive angle interventions to improve aqueous humor outflow. The research team will utilize imaging techniques to monitor the healing of the anterior chamber angle tissues post-surgery. By employing methods such as laser peripheral iridotomy and goniosynechialysis, the study aims to enhance understanding and standardization of these surgical techniques. The goal is to track biometric changes that may lead to better outcomes for patients suffering from angle-closure glaucoma.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Glaucoma patients eligible for standalone or combined angle intervention surgeries, such as LPI, LPIP, goniosynechialysis, trabeculotomy alone or combined with surgical iridectomy or phacoemulsification and intraocular lens implantation;
* Patients capable of undergoing preoperative examinations including CASIA2-OCT (anterior segment OCT), UBM, slit-lamp gonioscopy, IOL Master (or other optical biometry);
* Patients willing to participate in this study, signing informed consent, and agreeing to follow-up according to the study protocol.

Exclusion Criteria:

* Patients with severe ocular conditions such as corneal infection, ulcer, trauma, ocular tumors, retinal vascular occlusion, and retinal detachment;
* Those with various types of eye diseases that affect ocular parameter acquisition or interfere with visual field examination;
* Long-term local or systemic use of glucocorticoids;
* Patients with severe systemic diseases;
* Pregnant or lactating women;
* Unable to complete 12-month postoperative follow-up.

Where it's running

• Zhongshan ophthalmic center
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Principal investigator: Xinbo Gao, MD — State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University
• Study coordinator: Xinbo Gao, MD
• Email: gaoxb@mail.sysu.edu.cn
• Phone: +8618319579657

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Balance training for people with glaucoma

  A randomized study tests whether a structured eight-week balance program helps adults with glaucoma improve balance, reduce fall risk, and lessen fear of falling.

  Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Küçükçekmece, Istanbul · NCT07910955

• Eye drops Rhopressa vs Timolol to protect nerve cells in glaucoma

  In adults with open-angle glaucoma, this study tests whether Rhopressa helps preserve retinal nerve cells better than Timolol while both lower eye pressure.

  Recruiting Phase 4 Indiana University · Bloomington, Indiana · NCT07847073

• Comparison of FT-1000 non-contact tonometry with Goldmann applanation tonometry in glaucoma patients

  This study tests whether the FT-1000 non-contact tonometer gives measurements that agree with the Goldmann applanation tonometer in adults with glaucoma.

  Recruiting Tomey Corporation · Jacksonville, Florida · NCT07804277

• Removing the ripcord from a glaucoma drainage device after 3 months

  This study tests whether removing the ripcord from an implanted glaucoma drainage device changes eye pressure for adults with open-angle glaucoma.

  Recruiting Duke University · Durham, North Carolina · NCT07803536

• Glaucoma and Brain Changes: How Brain Structure and Size See What Glaucoma Is Doing

  This study tests whether glaucoma is linked to broader brain changes by comparing brain MRI and eye health over time in people with glaucoma and matched controls.

  Recruiting University Hospital, Bordeaux · Bordeaux · NCT07802769

• Long-Term Results After Ab-interno Trabeculotomy for Glaucoma

  This study tests whether ab-interno trabeculotomy with the Trabectome can provide sustained intraocular pressure reduction in glaucoma patients who had the procedure between 2019 and 2021.

  Recruiting Wuerzburg University Hospital · Würzburg, Bavaria · NCT07780916

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.