Observing brain networks in patients with epilepsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the structural and functional connectome of patients diagnosed with epilepsy. By analyzing brain networks through MRI scans and resting state EEG recordings, the study seeks to understand how these networks differ in individuals with focal or generalized epilepsy compared to healthy controls. The research focuses on the concept of the epileptogenic network, moving beyond traditional views of epilepsy that centered solely on the epileptogenic zone. Participants will undergo neuropsychological assessments to further explore the relationship between brain connectivity and epilepsy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* a diagnosis of focal or generalized epilepsy confirmed by specialist evaluation;
* at least one MRI scan of the brain that includes T1w
* at least one recording with resting state EEG
* age between 6 and 65 years at the time of the evaluation of the present study;
* ability to take part in a neuropsychological assessment.

Exclusion Criteria:

* vascular causes or non-low grade tumors as causes of epilepsy
* age different from the range 6-65 years
* neuroradiologic examination not complete
* absence of resting state recording
* inability to take part in a neuropsychological evaluation.

Where it's running

• IRCCS E.Medea
  Conegliano, Treviso, Italy Recruiting

Study contacts

• Principal investigator: Gian Marco Duma, PhD — IRCCS E. Medea
• Study coordinator: Gian Marco Duma, PhD
• Email: gianmarco.duma@lanostrafamiglia.it
• Phone: +39 0438414248

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.