Observing blood biomarkers in children with amblyopia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the predictive effect of plasma biomarkers on treatment outcomes in children diagnosed with amblyopia. It will involve children aged 3 to 12 years who are undergoing standard amblyopia treatment, with follow-up visits every three months. The study also seeks to explore the mechanisms of neuromodulation in the visual development of these children. By analyzing blood samples, researchers hope to identify biomarkers that can predict treatment success.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with amblyopia
* 3-12 years of age
* Able to tolerate amblyopia treatment
* Agree to be involved in this study and agree to have a follow up visit every 3 months.

Exclusion Criteria:

* Have previous treatment history before
* Have pathological ocular anomalies known to cause reduced visual acuity
* Have previous psychiatric, visual or neurological disorders
* Have eccentric fixation and/or abnormal retinal correspondence
* Have attention disorder and learning disability that cannot comprehend psychophysical test instructions given and/or consent for themselves

Where it's running

• Zhongshan Ophthalmic Center
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Jinrong Li, PhD
• Email: lijingr3@mail.sysu.edu.cn
• Phone: 86-020-87330351

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Psilocybin-assisted therapy to help adults with amblyopia see more clearly

  This study tests whether a single or small doses of psilocybin can boost the effectiveness of amblyopia treatment in adults.

  Recruiting Phase 1/2 Johns Hopkins University · Baltimore, Maryland · NCT07920081

• Augmented Reality Binocular Therapy for Adult Amblyopia

  This trial tests a home-based augmented reality binocular therapy to see if it improves vision in adults 18–40 with anisometropic amblyopia, compared with placebo training.

  Recruiting at 2 sites Polytechnic Institute of Porto · Coimbra, Coimbra District and 1 other locations · NCT07819552

• Gabor-based visual training for adults with amblyopia

  This study tests a computer-based Gabor training program to see if it can improve vision in adults aged 18–39 with amblyopia due to anisometropia or strabismus.

  Recruiting Shanghai Eye Disease Prevention and Treatment Center · Shanghai · NCT07764198

• Noninvasive brain stimulation plus augmented reality vision therapy for anisometropic amblyopia in adults

  This trial tests whether adding HD-tDCS to AR-based dichoptic therapy can improve vision in adults with anisometropic amblyopia.

  Recruiting at 2 sites Polytechnic Institute of Porto · Coimbra, Coimbra District and 1 other locations · NCT07752433

• tDCS for paediatric amblyopia

  This study tests whether non-invasive brain stimulation (tDCS) can improve vision for children aged 4–14 with amblyopia who didn’t get enough help from patching.

  Recruiting Universidad de Murcia · Murcia · NCT07547670

• Gamified visual training with occlusion for kids with anisometropic amblyopia

  This trial tests two kid-friendly digital games plus patching to see if they improve vision and motivation in children aged 4–7 with anisometropic amblyopia compared with patching alone.

  Recruiting Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07472231

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.