Observational study on pulmonary hypertension in China
Official title: A Observational Study in Chinese Patients With Pulmonary Hypertension (PH)
Run by The First Affiliated Hospital of Guangzhou Medical University · NCT05958901 · Data updated 2026-11-12
This study is trying to gather information from a large group of people with pulmonary hypertension in China to see how to better diagnose and treat their condition over five years.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 70 Years |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | The First Affiliated Hospital of Guangzhou Medical University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | July 12, 2023 |
| Main results expected | December 30, 2025 |
| Study ends | December 30, 2027 |
| Registry record updated | July 25, 2023 |
| Trial ID | NCT05958901 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with pulmonary hypertension, characterized by a mean pulmonary artery pressure greater than 25mmHg at rest or greater than 30mmHg during exercise.
✕Probably not a fit
Patients with acute exacerbations, severe respiratory diseases, or recent significant medical interventions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to establish a large cohort of patients with pulmonary hypertension (PH) in China, along with a biological database to support precision medicine. By collecting data on patients with PH, the study seeks to optimize diagnosis and treatment options tailored to individual needs. Participants will be monitored over a period of five years to gather comprehensive information on their condition and treatment responses.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and personalized treatment strategies for patients with pulmonary hypertension.
How similar studies have gone: While observational studies on pulmonary hypertension exist, this specific approach to creating a large cohort and biological database in China is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * PH group: When the mean pulmonary artery pressure is greater than 25mmHg at rest or greater than 30mmHg during exercise. * Signed informed consent obtained prior to participations with the ability to comply with protocol and be available for study visits over 5 years. Exclusion Criteria: * Acute exacerbation in the past 3 months Having other respiratory diseases with massive lung tissue destruction such as severe bronchiectasis and tuberculosis, etc. * Serious uncontrolled diseases thoracic or abdominal surgery in the last 3 months. * Eye surgery in the last three months. * Retinal detachment myocardial infarction in the last 3 months. * Admission to hospital for any cardiac condition in the last month. * Heart rate over 120 beats per minute. * Antibacterial chemotherapy for tuberculosis pregnant or breast feeding.
Where it's running
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The First Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.