Clinical trial Recruiting at 1 site Observational Ages 18 and up

Observational study on precision medicine for advanced cancer patients

Official title: Prospective Observational Study of a Precision Medicine Approach in Patients With Advanced Cancer

Run by Charite University, Berlin, Germany · NCT05926284 · Data updated 2026-11-12

This study is testing how personalized treatments based on genetic information can help people with advanced cancer feel better and improve their care.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment2000 (estimated)
SponsorCharite University, Berlin, Germany
Academic / other
Locations1 site (Berlin)
StatusRecruiting
StartedMarch 1, 2016
Main results expectedMarch 1, 2030
Study endsMarch 1, 2031
Registry record updatedJuly 3, 2023
Trial IDNCT05926284 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals diagnosed with advanced cancer who can provide informed consent and are eligible for targeted treatments based on molecular analysis.

Probably not a fit

Patients who are unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with advanced cancer who are undergoing extensive molecular sequencing as part of a precision oncology program at Charité University Medicine in Berlin. Participants will be registered and monitored to evaluate the effectiveness of individualized therapies and the clinical relevance of identified molecular alterations. The study aims to gather data on the frequency of these alterations and the utility of novel molecular analysis tools in guiding treatment decisions.

Why it matters

Potential benefit: If successful, this approach could lead to more effective, personalized treatment options for patients with advanced cancer.

How similar studies have gone: Other studies utilizing precision medicine approaches in oncology have shown promising results, indicating potential for success in this novel application.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* advanced cancer
* ability to give written informed consent
* performance status allows initiation of a potential targeted treatment after molecular analysis
* molecular analysis has been done or planned

Exclusion Criteria:

\- unable to give written informed consent

Where it's running

  • Charité Comprehensive Cancer Center
    Berlin, Germany
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.