Observational study on postpartum hypertension
Swiss Postpartum Hypertension Cohort (Swiss-PPHT)
This study looks at how high blood pressure after giving birth affects women's heart and kidney health over time and tries to find out what factors might increase their risk.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 480 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | University Hospital, Basel, Switzerland Academic / other |
| Locations | 1 site (Basel) |
| Trial ID | NCT04690660 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the short-, intermediate-, and long-term effects of postpartum hypertension, focusing on identifying predictors and risk factors associated with cardiovascular and renal health. It involves data collection on blood pressure measurements, organ damage markers, and patient-reported outcomes. Additionally, there will be a home-based blood pressure management substudy to evaluate current disease management strategies.
Who should consider this trial
Good fit: Ideal candidates include women with hypertensive disorders during pregnancy, including those with postpartum hypertension or preexisting hypertension.
Not a fit: Patients who delivered more than 14 days prior or those unable to provide consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management and outcomes for women experiencing postpartum hypertension.
How similar studies have performed: While there have been studies on postpartum hypertension, this specific observational approach focusing on long-term outcomes and home monitoring is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * all women with hypertensive disorders of pregnancy * postpartum hypertension (blood pressure measurements of systolic ≥140 and/or diastolic ≥ 90mmHg or antihypertensive therapy within the first 14 days after delivery) * women with preexisting hypertension or * women on antihypertensive medication Exclusion Criteria: * delivery \> 14 days * lack of consent to participate in the study, language barriers or lack of general understanding
Where this trial is running
Basel
- Medical Outpatient Department and Hypertension Clinic, University Hospital Basel — Basel, Switzerland (Recruiting)
Study contacts
- Principal investigator: Thenral Socrates, Dr. med. — Medical Outpatient Department and Hypertension Clinic, University Hospital BaselUni
- Study coordinator: Thenral Socrates, Dr. med.
- Email: thenral.socrates@usb.ch
- Phone: +41 61 328 6647
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.