Clinical trial Recruiting at 1 site Observational Ages 18 and up Women only

Observational study on postpartum hypertension

Official title: Swiss Postpartum Hypertension Cohort (Swiss-PPHT)

Run by University Hospital, Basel, Switzerland · NCT04690660 · Data updated 2026-11-12

This study looks at how high blood pressure after giving birth affects women's heart and kidney health over time and tries to find out what factors might increase their risk.

Quick facts

Study typeObservational
Ages18 Years and up
SexWomen only
Enrollment480 (estimated)
SponsorUniversity Hospital, Basel, Switzerland
Academic / other
Locations1 site (Basel)
StatusRecruiting
StartedJune 4, 2020
Main results expectedMay 2030
Study endsMay 2030
Registry record updatedMay 28, 2025
Trial IDNCT04690660 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include women with hypertensive disorders during pregnancy, including those with postpartum hypertension or preexisting hypertension.

Probably not a fit

Patients who delivered more than 14 days prior or those unable to provide consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the short-, intermediate-, and long-term effects of postpartum hypertension, focusing on identifying predictors and risk factors associated with cardiovascular and renal health. It involves data collection on blood pressure measurements, organ damage markers, and patient-reported outcomes. Additionally, there will be a home-based blood pressure management substudy to evaluate current disease management strategies.

Why it matters

Potential benefit: If successful, this study could lead to improved management and outcomes for women experiencing postpartum hypertension.

How similar studies have gone: While there have been studies on postpartum hypertension, this specific observational approach focusing on long-term outcomes and home monitoring is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* all women with hypertensive disorders of pregnancy
* postpartum hypertension (blood pressure measurements of systolic ≥140 and/or diastolic ≥ 90mmHg or antihypertensive therapy within the first 14 days after delivery)
* women with preexisting hypertension or
* women on antihypertensive medication

Exclusion Criteria:

* delivery \> 14 days
* lack of consent to participate in the study, language barriers or lack of general understanding

Where it's running

  • Medical Outpatient Department and Hypertension Clinic, University Hospital Basel
    Basel, Switzerland
    Recruiting

Study contacts

  • Principal investigator: Thenral Socrates, Dr. med. — Medical Outpatient Department and Hypertension Clinic, University Hospital BaselUni
  • Study coordinator: Thenral Socrates, Dr. med.
  • Email: thenral.socrates@usb.ch
  • Phone: +41 61 328 6647

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.