Observational study on multi-cancer detection testing

Multi-Cancer Detection Observational Cohort Study

Observational Mayo Clinic · NCT06962995

This study is testing how well a new blood test for detecting multiple types of cancer works in real-life settings and how it affects patient care.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages21 Years and up
SexAll
SponsorMayo Clinic Academic / other
Locations3 sites (Scottsdale, Arizona and 2 other locations)
Trial IDNCT06962995 on ClinicalTrials.gov

What this trial studies

This observational study evaluates the integration of Multi-Cancer Detection (MCD) testing into clinical practice to understand its application and effects in real-world settings. Participants will provide blood samples and complete surveys to gather data on the use of MCD testing. The study aims to assess how effectively this testing can identify various types of cancer and its impact on patient management. By analyzing the outcomes, the study seeks to inform future clinical practices regarding cancer detection.

Who should consider this trial

Good fit: Ideal candidates are adults aged 21 and older who have undergone or are scheduled to undergo a multi-cancer detection test at Mayo Clinic.

Not a fit: Patients currently undergoing active cancer treatment or those with invasive cancer diagnosed within the last 3 years may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance early cancer detection and improve patient outcomes through timely interventions.

How similar studies have performed: Other studies have shown promise in the effectiveness of multi-cancer detection approaches, indicating potential for success in this observational study.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Has Mayo Clinic medical record number
* Has undergone (within last 6 months) or scheduled to undergo a multi-cancer detection test (MCD) as ordered by provider
* Able to provide informed consent
* ≥ 21 years old
* Ability to provide blood sample

Exclusion Criteria:

* Individuals who have situations that would limit compliance with the study requirements
* Institutionalized (i.e. Federal Medical Prison)
* Known pregnancy (self-reported)
* Currently undergoing active cancer treatment other than adjuvant hormone therapy
* Invasive cancer diagnosis within the last 3 years

Where this trial is running

Scottsdale, Arizona and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.