Observational study on liver transplantation using hypothermic oxygenated machine perfusion

Vienna Hypothermic Oxygenated Machine Perfusion for Liver Transplantation Study

Observational Medical University of Vienna · NCT06418165

This study looks at how well a new method of preserving livers with a special machine helps patients who are getting liver transplants at the Medical University of Vienna.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorMedical University of Vienna Academic / other
Locations1 site (Vienna)
Trial IDNCT06418165 on ClinicalTrials.gov

What this trial studies

This observational cohort study aims to collect and analyze data from patients undergoing liver transplantation utilizing hypothermic oxygenated machine perfusion at the Medical University of Vienna. The study will prospectively record patient outcomes to evaluate both short- and long-term results associated with this innovative preservation technique. By focusing on a specific patient population, the study seeks to enhance understanding of the efficacy and safety of this method in liver transplantation.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who are scheduled for liver transplantation using hypothermic oxygenated machine perfusion.

Not a fit: Patients who are pregnant, those receiving partial grafts, or individuals with compromised anatomical integrity of the liver will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve outcomes for patients undergoing liver transplantation by optimizing organ preservation techniques.

How similar studies have performed: While this approach is being explored, the specific application of hypothermic oxygenated machine perfusion in liver transplantation is still under investigation, indicating a novel area of research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients undergoing liver transplantation with the use of hypothermic oxygenated machine perfusion
* age ≥ 18 years

Exclusion Criteria:

* pregnancy
* partial grafts
* the anatomical integrity of the liver is not preserved in a way that makes the perfusion of the liver possible

Where this trial is running

Vienna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions End Stage Liver DiseaseHepatocellular CarcinomaLiver TransplantationHypothermic Oxygenated Machine Perfusion
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.