Clinical trial Recruiting at 1 site Observational Ages 65 and up

Observational study on eye health in the elderly

Official title: The Proactive Ophthalmic Examination Cohort of Older Adults

Run by Zhongshan Ophthalmic Center, Sun Yat-sen University · NCT05851287 · Data updated 2026-11-12

This study is looking at how lifestyle and genetics affect eye health in older people to help understand the risks for common eye diseases like glaucoma and macular degeneration.

Quick facts

Study typeObservational
Ages65 Years and up
SexAll
Enrollment5000 (estimated)
SponsorZhongshan Ophthalmic Center, Sun Yat-sen University
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedFebruary 20, 2023
Main results expectedFebruary 19, 2033
Study endsFebruary 19, 2034
Registry record updatedJune 9, 2026
Trial IDNCT05851287 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are elderly individuals over 60 years old with normal vision and no significant ocular diseases.

Probably not a fit

Patients with existing ocular diseases or those who have undergone recent eye surgeries may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to establish a cohort of elderly individuals with normal vision and ocular structure to investigate the risk factors for common eye diseases such as glaucoma and age-related macular degeneration. Participants will undergo yearly examinations for at least five years to collect clinical and genomic data. The focus is on understanding how lifestyle changes and genetics impact eye health in the aging Chinese population. The findings will provide valuable insights for future clinical studies on eye diseases.

Why it matters

Potential benefit: If successful, this study could lead to better prevention and management strategies for eye diseases in the elderly.

How similar studies have gone: Other studies focusing on aging and eye health have shown promising results, indicating that this approach is supported by previous research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Aged 65 years or older

Exclusion Criteria:

* Unable to complete required systemic or ophthalmic examinations due to frailty, poor general health, or other physical limitations
* Refusal to participate in the study

Where it's running

  • Zhongshan Ophthalmic Center, Sun Yat-sen University
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.