Observational study on eye health in the elderly
The Cohort Study of Eye Health of Aging People
Zhongshan Ophthalmic Center, Sun Yat-sen University · NCT05851287
This study is looking at how lifestyle and genetics affect eye health in older people to help understand the risks for common eye diseases like glaucoma and macular degeneration.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2500 (estimated) |
| Ages | 60 Years to 95 Years |
| Sex | All |
| Sponsor | Zhongshan Ophthalmic Center, Sun Yat-sen University (other) |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT05851287 on ClinicalTrials.gov |
What this trial studies
This study aims to establish a cohort of elderly individuals with normal vision and ocular structure to investigate the risk factors for common eye diseases such as glaucoma and age-related macular degeneration. Participants will undergo yearly examinations for at least five years to collect clinical and genomic data. The focus is on understanding how lifestyle changes and genetics impact eye health in the aging Chinese population. The findings will provide valuable insights for future clinical studies on eye diseases.
Who should consider this trial
Good fit: Ideal candidates are elderly individuals over 60 years old with normal vision and no significant ocular diseases.
Not a fit: Patients with existing ocular diseases or those who have undergone recent eye surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better prevention and management strategies for eye diseases in the elderly.
How similar studies have performed: Other studies focusing on aging and eye health have shown promising results, indicating that this approach is supported by previous research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: 1. Be able and willing to consent to the qualification and the follow-up phases of the study; 2. Be able to undergo yearly examinations for ≥5 years; 3. Age is older than 60 years; 4. Best-corrected visual acuity of both eyes is better than 20/32; 5. Intraocular pressure (non-contact tonometer) is between 10-21 mmHg; 6. Except for mild cataracts, no other structural abnormalities of the eye are found. 7. have fundus photographs of adequate quality as assessed with a standardized protocol by the University of Wisconsin Fundus Photograph Reading Center. Exclusion Criteria: 1. the presence of ocular disease in either eye, except for mild cataracts and ametropia; 2. previous retinal or other ocular surgical procedures (other than cataract extraction and capsulotomy); 3. a chronic requirement for any systemic or ocular medication administered for other diseases and known to be toxic to the retina or optic nerve; 4. cataract surgery within three months or capsulotomy within six weeks before the qualification visit; 5. any systemic disease with a poor 5-year survival prognosis.
Where this trial is running
Guangzhou, Guangdong
- Zhongshan Ophthalmic Center, Sun Yat-sen University — Guangzhou, Guangdong, China (RECRUITING)
Study contacts
- Study coordinator: Xun Wang, M.D.
- Email: wangx48@mail2.sysu.edu.cn
- Phone: +8615017541549
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Eye Diseases, Elderly population, Common eye disease, Risk factor, Genetics