Observational study on epilepsy using real-world data
Official title: An Observational Study of Epilepsy: Biology and Outcomes Using Real-world Data
Run by Cardiff and Vale University Health Board · NCT05632978 · Data updated 2026-11-12
This study is trying to collect and analyze health information and blood samples from people with epilepsy to better understand their condition and find potential markers that could help in treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 16 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Cardiff and Vale University Health Board Government |
| Locations | 1 site (Cardiff) |
| Status | Recruiting |
| Started | April 24, 2023 |
| Main results expected | December 2032 |
| Study ends | December 2032 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT05632978 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 16 and older who are being investigated for epilepsy and are under the care of the epilepsy unit at Cardiff & Vale University Health Board.
✕Probably not a fit
Patients who are not currently being investigated for epilepsy or are outside the age range may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to gather and analyze clinical and biological data from individuals with epilepsy receiving care at the Cardiff & Vale University Health Board. Participants will consent to the use of their routine clinical data and provide biological samples, such as blood, during their clinic visits. The study will utilize quantitative methods to explore various phenotypic, genetic, biochemical, neurophysiological, and radiological patterns associated with epilepsy. By building a comprehensive disease register, the study seeks to enhance understanding of epilepsy outcomes and potential biomarkers.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding of epilepsy and better-targeted treatments for patients.
How similar studies have gone: Other studies utilizing real-world data in epilepsy have shown promise in understanding disease patterns, suggesting this approach could be beneficial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individual is being investigated for epilepsy and under the clinical care of the epilepsy unit at Cardiff \& Vale University Health Board or regional clinics in Cwm Taf. * Individual is at least 16 years old. * Informed consent sought and given by individual. Exclusion Criteria: * None
Where it's running
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Cardiff and Vale UHB
Cardiff, United Kingdom Recruiting
Study contacts
- Principal investigator: Khalid Hamandi — Cardiff & Vale University Health Board
- Study coordinator: Khalid Hamandi
- Email: khalid.hamandi@wales.nhs.uk
- Phone: +44(0)2921843454
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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A one-day study tests how an acute bout of exercise changes brain function and bodily signals in people with certain neurological conditions compared with healthy individuals.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.