Observational study on chronic liver disease progression and prognosis
Multicenter, Retrospective-prospective, Observational Clinical Study of the Natural Course and Long-term Prognosis of Patients With Chronic Liver Disease
This study looks at how chronic liver disease progresses and what affects patients' long-term health to help improve care for those living with the condition in China.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50000 (estimated) |
| Sex | All |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University Academic / other |
| Locations | 1 site (Xi'an) |
| Trial ID | NCT05653830 on ClinicalTrials.gov |
What this trial studies
This observational study aims to construct a retrospective-prospective cohort of patients with chronic liver disease by establishing a multicenter collaborative network. It will analyze the disease characteristics, progression patterns, clinical features, and long-term prognosis of chronic liver disease caused by various etiologies. The study focuses on improving clinical data related to chronic liver disease in China, which is crucial for better patient management and future epidemiological studies. By following patients over the long term, the study seeks to enhance understanding of this public health issue.
Who should consider this trial
Good fit: Ideal candidates include patients diagnosed with chronic liver disease who regularly visit liver disease centers.
Not a fit: Patients with hepatocellular carcinoma or those who have undergone liver transplantation will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management and treatment strategies for patients with chronic liver disease.
How similar studies have performed: While similar observational studies have been conducted, this specific multicenter approach focusing on chronic liver disease in China is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:
1. Patients who regularly visit and follow up at the corresponding liver disease center
2. All patients meet at least one of the following diagnostic criteria for chronic liver disease:
* Chronic viral hepatitis B
* Chronic viral hepatitis C ③. Chronic viral hepatitis D ④. Autoimmune liver disease (PBC/AIH/PSC) ⑤. Non-alcoholic fatty liver disease ⑥. Alcoholic liver disease
Exclusion Criteria:
1. First visit diagnosed with hepatocellular carcinoma or after liver transplantation.
2. Combined with other advanced malignant tumors.
3. The patient refused to sign the informed consent form to participate in this study.
Where this trial is running
Xi'an
- First Affiliated Hospital Xi'an Jiaotong University — Xi'an, China (Recruiting)
Study contacts
- Study coordinator: Xiaonan Wu
- Email: w793402903@163.com
- Phone: 008615686231404
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.