Observational study on brain calcification characteristics
A Registered Cohort Study on Brain Calcification
This study is trying to learn more about brain calcification by looking at patients with calcium deposits in their brains, their family members, and healthy individuals to see how it affects health over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Sex | All |
| Sponsor | First Affiliated Hospital of Fujian Medical University Academic / other |
| Locations | 1 site (Fuzhou, Fujian) |
| Trial ID | NCT04010201 on ClinicalTrials.gov |
What this trial studies
This study aims to establish a cohort of patients with brain calcification to investigate their clinical and genetic characteristics. It will include patients with brain calcium deposits identified through CT scans, as well as their relatives and unrelated healthy controls. The study will follow these participants over time to gather data on the natural history of brain calcification and its potential associations with various disorders. By understanding these factors, the study seeks to shed light on the implications of brain calcification in different populations.
Who should consider this trial
Good fit: Ideal candidates include patients with brain calcium deposits as identified by CT scans, their relatives, and unrelated healthy controls.
Not a fit: Patients with brain calcification due to specific secondary factors such as infections, poisoning, or trauma may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of brain calcification and its implications for various neurological conditions, potentially leading to improved patient management.
How similar studies have performed: While there may be studies on brain calcification, this cohort approach focusing on genetic and clinical characteristics is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with brain calcium deposit(s) based on examinations of CT scans * Patients with total calcification score(TCS) greater than the physiological threshold * Relatives of brain calcification patients. * Unrelated healthy controls * Participants or Parent(s)/legal guardian(s) willing and able to complete the informed consent process Exclusion Criteria: * Brain calcification caused by specific secondary factors such as infection, poisoning, and trauma * Participants declining or unable to comply with trial procedures and visit schedule
Where this trial is running
Fuzhou, Fujian
- Department of Neurology, First Affiliated Hospital Fujian Medical University — Fuzhou, Fujian, China (Recruiting)
Study contacts
- Study coordinator: Yi Lin, PhD
- Email: linyi7811@163.com
- Phone: 86-0591-87982772
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.