Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using AI language models to help diagnose and recommend treatments for urologic conditions

Official title: Evaluation of AI Large Models for Diagnosis and Treatment in Real-World Cases: Multicenter Retrospective Study

Run by First Affiliated Hospital of Fujian Medical University · NCT07378358 · Data updated 2026-11-12

This project will test whether three AI language models (ChatGPT, Gemini, DeepSeek) can accurately recognize urologic diseases and suggest diagnoses and treatments from archived hospital records of adult patients.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment800 (estimated)
SponsorFirst Affiliated Hospital of Fujian Medical University
Academic / other
Locations1 site (Fuzhou)
StatusRecruiting
StartedJanuary 1, 2026
Main results expectedApril 1, 2026
Study endsJune 1, 2026
Registry record updatedJanuary 30, 2026
Trial IDNCT07378358 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adult patients (18+) whose complete inpatient urology medical records from the participating hospitals are archived and available with consent.

Probably not a fit

Patients without complete medical records, those under 18, or cases with complex individualized needs not captured in records are unlikely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter retrospective project will run three large language models—ChatGPT, Gemini, and DeepSeek—on 800 archived inpatient urology records from four tertiary hospitals to compare model outputs to documented diagnoses and treatment plans. Model-generated disease recognition, preliminary diagnoses, and treatment recommendations will be compared against the original clinical records and discharge decisions to measure accuracy and applicability. Data will be anonymized and used with prior patient or legal representative consent, and cases with missing core information will be excluded. The aim is to map strengths and limitations of LLM-based decision support in real-world clinical documentation.

Why it matters

Potential benefit: If successful, these AI models could provide faster, more consistent decision support for clinicians, potentially improving diagnosis and treatment planning in urology.

How similar studies have gone: Early research shows LLMs can perform well on some diagnostic and clinical reasoning tasks, but real-world retrospective validations are limited and results have been mixed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The case data is sourced from the four hospitals involved in the study, with complete and authentic diagnosis and treatment records.
* Patients must be 18 years or older, with no gender restrictions.
* Complete medical records, including the following core information: patient' s basic information, present illness history, past medical history, physical examination, and auxiliary examinations (including laboratory and imaging tests).
* A clear discharge diagnosis and treatment plan (including therapeutic measures and follow-up arrangements).
* Medical records have been archived, with objective and accurate information that has not been altered.
* The patient or their legal representative has provided informed consent, agreeing to the use of their anonymized medical data for research analysis.

Exclusion Criteria:

* Medical records with significant missing information, such as key clinical details (present illness history, diagnostic or treatment records, etc.).
* Cases where the diagnosis or treatment plan is unclear, or where treatment has not been fully completed for an initial diagnosis.
* Cases where the primary diagnosis is not urological.
* Cases with major errors or inconsistencies in the records that could affect further assessment.
* Medical records in special formats or images that are not readable (e.g., handwritten notes, non-standard documentation).
* Patients who have not signed the informed consent form or who refuse to allow their medical data to be used for research.

Where it's running

  • The First Affiliated Hospital of Fujian Medical University
    Fuzhou, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Urine, perineal, and stool microbiota in children and adolescents

    We will test whether the bacteria in voided urine, around the genitals, and in stool differ between children with overactive bladder or daytime wetting and healthy children of the same age and gender.

    Recruiting at 2 sites Aalborg University Hospital · Aalborg and 3 other locations · NCT07535619

  • 21-day comprehensive spa care for kidney and urinary conditions

    This program will try a 21-day spa treatment with mineral water baths, drinking cures, exercise and diet for adults 40–70 who have chronic kidney or urinary problems to see if it improves symptoms and kidney health.

    Recruiting Institute of Spa and Balneology, public research institution · Mariánské Lázně, Carlsbad Region · NCT07435844

  • Hospital admissions for blood in the urine

    This international observational project will look at how hospitals manage adults admitted with blood in the urine to see which approaches lead to shorter stays and better outcomes.

    Recruiting British Urology Researchers in Surgical Training · London · NCT07395037

  • Virtual reality to reduce pain and anxiety during outpatient urology procedures

    This trial will try a virtual reality headset (REALICA®) to reduce pain and anxiety for adults having outpatient urology procedures such as circumcision, prostate biopsy, or flexible cystoscopy.

    Recruiting Istituto Oncologico Veneto IRCCS · Padova · NCT07338292

  • Using vorolanib for treating advanced kidney cancer

    This study is testing if the drug vorolanib can help people with advanced kidney cancer live longer when used as a second treatment option.

    Recruiting Jinling Hospital, China · Nanjing, Jiangsu · NCT06676527

  • Improving quality of life for patients undergoing urological surgery

    This study is testing whether using personalized questionnaires can help improve the quality of life and recovery for patients having urological surgery.

    Recruiting Medical University of Graz · Graz, Styria · NCT06397287

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.