Observational registry for children with rheumatic diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry continues the work of the CARRA Registry, which collects data on pediatric patients with rheumatic diseases to support future research. It aims to answer critical questions regarding the safety and effectiveness of various therapeutics used in treating these conditions. The registry engages families and communities to ensure comprehensive participation and data collection across multiple sites. The Duke Clinical Research Institute coordinates the registry, facilitating high-quality clinical and translational research.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Onset of rheumatic disease prior to age 16 years for JIA and onset prior to age 19 years for all other rheumatic diseases (see appendix A).
2. Subject (and/or parent/legal guardian when required) is able to provide written informed consent and willing to comply with study procedures.
3. Subject and/or parent/legal guardian is willing to be contacted in the future by study staff.

Exclusion Criteria:

1\. Greater than 21 years of age at the time of enrollment.

Where it's running

• University of Alabama at Birmingham
  Birmingham, Alabama, United States Recruiting
• Phoenix Children's Hospital
  Phoenix, Arizona, United States Recruiting
• Mattel Children's Hospital at University of California Los Angeles
  Los Angeles, California, United States Recruiting
• Stanford University Medical Center
  Palo Alto, California, United States Recruiting
• Rady Children's Hospital San Diego
  San Diego, California, United States Recruiting
• University of California at San Francisco Medical Center
  San Francisco, California, United States Recruiting

+32 more sites. See ClinicalTrials.gov for the full list.

Study contacts

• Principal investigator: Mara L Becker, MD, MSCE — Duke Clinical Research Insitute
• Study coordinator: Mara L Becker, MD, MSCE
• Email: mara.becker@duke.edu
• Phone: (919) 419-5032

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Stop penicillin in children with mild rheumatic heart disease to see if it’s still safe

  This study tests whether stopping secondary antibiotic prophylaxis is no worse than continuing it for 2 years in kids and teens with mild rheumatic heart disease who have already been treated.

  Recruiting Phase 3 Children's Hospital Medical Center, Cincinnati · Kampala, UG · NCT07146048

• Korea VHD Echo Study: Real-World Practice of Aortic, Mitral, and Tricuspid Valves

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• Treating severe mitral valve calcification with a specialized balloon

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  Recruiting Prince of Wales Hospital, Shatin, Hong Kong · Shatin, New Territories · NCT06952374

• Screening for Rheumatic Heart Disease in Rural Communities

  This study is testing if using ultrasound to screen for Rheumatic Heart Disease in rural communities can help find and treat the condition early to improve health outcomes.

  Recruiting National Institute of Cardiovascular Diseases, Pakistan · Karachi, Sindh · NCT05991219

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.