Observational cohort for systemic lupus erythematosus in Saudi Arabia
National Systemic Lupus Erythematosus Prospective Cohort, Saudi Arabia
This study is trying to learn more about systemic lupus erythematosus in Saudi Arabia by following patients to see how the disease shows up and changes over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 19 Years and up |
| Sex | All |
| Sponsor | King Saud University Academic / other |
| Locations | 1 site (Riyadh, Central Province) |
| Trial ID | NCT04604990 on ClinicalTrials.gov |
What this trial studies
This observational cohort aims to define systemic lupus erythematosus (SLE) in Saudi Arabia, a region with unique genetic factors due to high consanguinity. The study will follow an open cohort design to gather comprehensive data on disease presentation, progression, and outcomes. By collecting detailed immunological, molecular, genetic, and microbiome information, the study seeks to address the gaps in understanding SLE in this population, which has been primarily based on retrospective analyses. This prospective approach is expected to yield more reliable and relevant data for SLE management.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients over 18 years old who meet established classification criteria for systemic lupus erythematosus.
Not a fit: Patients who do not fulfill the classification criteria for systemic lupus erythematosus will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of systemic lupus erythematosus in Saudi Arabian patients.
How similar studies have performed: While there have been many retrospective studies on SLE, this prospective cohort approach is novel and has not been previously implemented in Saudi Arabia.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Adult patients defined as age greater than 18 years old. 2. Patients should fulfil one of the following classification criteria for SLE (ACR, SLICC or ACR/EULAR criteria). 3. No restriction on time of diagnosis. Exclusion Criteria: * Patients who don't fulfil classification criteria mentioned above.
Where this trial is running
Riyadh, Central Province
- king Saud University medical city — Riyadh, Central Province, Saudi Arabia (Recruiting)
Study contacts
- Study coordinator: Ibrahim Almaghlouth, MSc(c), AmBIM, FRCPC, FACR
- Email: ialmaghlouth@ksu.edu.sa
- Phone: 966544282266
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.