Nutritional support for gastric cancer patients after surgery
Effect of Oral Nutritional Supplement on Nutritional Status and Clinical Outcome in Gastric Cancer Patients After Total Gastrectomy
NA · Jinling Hospital, China · NCT05823272
This study tests if giving nutritional supplements to gastric cancer patients after surgery helps them recover better than just following a normal diet.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Jinling Hospital, China (other) |
| Locations | 1 site (Nanjing, Jiangsu) |
| Trial ID | NCT05823272 on ClinicalTrials.gov |
What this trial studies
This study focuses on gastric cancer patients who have undergone total gastrectomy and are at nutritional risk. Participants will be randomly assigned to receive either an oral nutritional supplement or a normal diet for six months after discharge. The study aims to evaluate the effects of the nutritional supplement on the patients' long-term nutritional status and overall recovery. Both groups will also receive nutrition counseling to support their dietary needs.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-80 who have undergone radical total gastrectomy and are identified as at nutritional risk.
Not a fit: Patients who are unable to consume oral nutrition supplements or have severe underlying health conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve the nutritional status and recovery outcomes for gastric cancer patients post-surgery.
How similar studies have performed: Previous studies have shown that nutritional supplementation can positively impact recovery in surgical patients, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Informed consent of patients or their legal representatives to participate in this study 2. consecutive adult (18-80 years) patients underwent radical gastrectomy (total gastrectomy) 3. nutrition Risk Screening (NRS) 2002≥3 at discharge 4. eastern Cooperative Oncology Group (ECOG) score of 0-2 at discharge 5. normal liver and kidney function Exclusion Criteria: 1. unable to oral or consume ONS 2. allergy to any ingredient in the oral nutrition powder 3. pregnancy 4. palliative surgery or gastric stump cancer 5. congenital acquired immune deficiency disease 6. severe liver and kidney diseases including active hepatitis, cirrhosis, and uremia diabetes has developed complications or uncontrolled by medications 7. motor system diseases cannot complete grip strength measurement and 5-time chair stand test 8. have cognitive impairment, unable to complete the relevant questionnaires 9. expected to require tube feeding after discharge from the hospital
Where this trial is running
Nanjing, Jiangsu
- Jinling Hospital, China — Nanjing, Jiangsu, China (RECRUITING)
Study contacts
- Principal investigator: Xinying Wang, MD — Jinling Hosptial
- Study coordinator: Tingting Gao, MS
- Email: gaotting77@163.com
- Phone: 15312311968
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gastric Cancer, Oral nutritional supplement, Sarcopenia, long-term nutritional status